Oral health in relation to all-cause mortality: the IPC cohort study
Oral health in relation to all-cause mortality: the IPC cohort study
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DOI：
10.1038/srep44604
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发表时间：
2017-03-15
影响因子：
4.6
通讯作者：
Bouchard, Philippe
中科院分区：
文献类型：
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作者：
Adolph, Margaux;Darnaud, Christelle;Bouchard, Philippe
我们评估了口腔健康和死亡率之间的关系。研究人群包括76188名年龄在16-89岁之间的受试者。平均随访时间为3.4±2.4年。有癌症或心血管疾病个人病史和意外死亡的受试者被排除在分析之外。进行全口临床检查，以评估牙菌斑，牙结石和牙龈炎症。在模型中累积牙齿数量和咀嚼功能单元（10个缺失牙齿和10个缺失咀嚼功能单元）（HR = 2.31, [95% CI: 1.40-3.82]）和咀嚼功能单元= 3个口腔疾病，全因死亡率（HR = 3.39, [95% CI: 2.51-5.42]）、全癌症死亡率（HR = 3.59, [95% CI: 1.23-10.05]）和非心血管和非癌症死亡率（HR = 4.71, [95% CI: 1.74-12.7]）的风险增加。本研究表明口腔健康与死亡率之间存在正线性关系。
We evaluated the association between oral health and mortality. The study population comprised 76,188 subjects aged 16-89 years at recruitment. The mean follow-up time was 3.4 +/- 2.4 years. Subjects with a personal medical history of cancer or cardiovascular disease and death by casualty were excluded from the analysis. A full-mouth clinical examination was performed in order to assess dental plaque, dental calculus and gingival inflammation. The number of teeth and functional masticatory units 10 missing teeth and functional masticatory units 10 missing teeth (HR = 2.31, [95% CI: 1.40-3.82]) and functional masticatory units = 3 oral diseases were cumulated in the model, the risk increased for all-cause mortality (HR = 3.39, [95% CI: 2.51-5.42]), all-cancer mortality (HR = 3.59, [95% CI: 1.23-10.05]) and non-cardiovascular and non-cancer mortality (HR = 4.71, [95% CI: 1.74-12.7]). The present study indicates a postive linear association between oral health and mortality.