Somitic origin of the medial border of the mammalian scapula and its homology to the avian scapula blade
Somitic origin of the medial border of the mammalian scapula and its homology to the avian scapula blade
复制标题
哺乳动物肩胛骨内侧缘的体节起源及其与鸟类肩胛骨的同源性
DOI：
10.1111/j.1469-7580.2009.01200.x
复制
发表时间：
2010
影响因子：
2.4
通讯作者：
K. Patel
中科院分区：
文献类型：
--
作者：
P. Valášek;S. Theis;E. Krejčí;M. Grim;F. Maina;Y. Shwartz;A. Otto;Ruijin Huang;K. Patel
肩胛骨是胸带的主要骨骼元素，允许前肢肌肉固定到中轴骨骼。脊椎动物肢体骨骼传统上被认为是由侧板中胚层发育而来，而肌肉系统则是由轴向体节发育而来。然而，在鸟类中，肩胛骨已经被证明是从体节发展而来的。我们调查是否体节的贡献也存在于哺乳动物肩胛骨。利用遗传谱系追踪技术，我们发现哺乳动物肩胛骨的内侧缘是由体节细胞发育而来的。肩胛骨内侧缘是带肌（前锯肌、菱形肌和肩胛提肌）的附着部位。我们表明，这些肌肉的发展是独立的机制，控制所有其他肢体肌肉的形成。我们建议，这些肌肉被具体称为内侧带肌。我们的研究结果建立了鸟类肩胛骨叶片和哺乳动物肩胛骨的内侧缘作为同源结构，因为它们具有相同的发育起源。
The scapula is the main skeletal element of the pectoral girdle allowing muscular fixation of the forelimb to the axial skeleton. The vertebrate limb skeleton has traditionally been considered to develop from the lateral plate mesoderm, whereas the musculature originates from the axial somites. However, in birds, the scapular blade has been shown to develop from the somites. We investigated whether a somitic contribution was also present in the mammalian scapula. Using genetic lineage‐tracing techniques, we show that the medial border of the mammalian scapula develops from somitic cells. The medial scapula border serves as the attachment site of girdle muscles (serratus anterior, rhomboidei and levator scapulae). We show that the development of these muscles is independent of the mechanism that controls the formation of all other limb muscles. We suggest that these muscles be specifically referred to as medial girdle muscles. Our results establish the avian scapular blade and medial border of the mammalian scapula as homologous structures as they share the same developmental origin.
DOI：
10.1073/pnas.93.9.4213
发表时间：
1996-04-30
影响因子：
11.1
作者：
Epstein, JA;Shapiro, DN;Maas, RL
通讯作者：
Maas, RL
鸟类肩胛骨的双重起源和节段组织。
DOI：
10.1242/dev.127.17.3789
发表时间：
2000
期刊：
Development (Cambridge, England)
影响因子：
--
作者：
Huang,R;Zhi,Q;Patel,K;Wilting,J;Christ,B
通讯作者：
Christ,B