Inhibitory effect of 13 taxane diterpenoids from Chinese yew (Taxus chinensis var. mairei) on the proliferation of HeLa cervical cancer cells
Inhibitory effect of 13 taxane diterpenoids from Chinese yew (Taxus chinensis var. mairei) on the proliferation of HeLa cervical cancer cells
复制标题
DOI：
10.1080/09168451.2016.1194182
复制
发表时间：
2016-01-01
影响因子：
1.6
通讯作者：
Kiyota, Hiromasa
中科院分区：
文献类型：
--
作者：
Liu, Hai-Sheng;Gao, Yu-Huan;Kiyota, Hiromasa
研究了从红豆杉中分离得到的13种紫杉烷类化合物对肿瘤生长的抑制作用。mairei）对人宫颈癌HeLa细胞增殖的影响。具有疏水性肉桂酸酯侧链的四种化合物显示出抗增殖活性，这可能是由于增加的细胞渗透性。
The inhibitory effect of 13 taxanes isolated from the Chinese yew (Taxus chinensis var. mairei) on the proliferation of human cervical cancer HeLa cells were examined using an MTT assay. Four compounds having a hydrophobic cinnamate side chain showed antiproliferative activity, which may be due to increased cell permeability.