US prevalence of self-reported peanut, tree nut, and sesame allergy: 11-year follow-up
US prevalence of self-reported peanut, tree nut, and sesame allergy: 11-year follow-up
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DOI：
10.1016/j.jaci.2010.03.029
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发表时间：
2010-06-01
影响因子：
14.2
通讯作者：
Sampson, Hugh A.
中科院分区：
文献类型：
--
作者：
Sicherer, Scott H.;Munoz-Furlong, Anne;Sampson, Hugh A.
背景：在美国，对花生和树坚果过敏（TNs）是致死性过敏反应的主要原因，而且患病率似乎在增加。目的：我们试图确定2008年美国自我报告的花生、TN和芝麻过敏的流行程度，并将结果与1997年和2002年进行的可比调查进行比较。方法：在全国范围内对花生和全氮过敏进行横断面随机电话调查，使用以前使用的问卷，并附加有关芝麻的问题。结果：共调查5300户（13534名受试者）（参与率为42%，2002年为52%，1997年为67%）。花生过敏、全谷氨酰胺过敏或两者兼而有之的受试者比例为1.4% (95% Cl， 1.2%至1.6%)，2002年为1.2%，1997年为1.4%。成人患病率为1.3% (95% CI, 1.1% - 1.6%)，与之前的调查结果无显著差异。然而，18岁以下儿童花生或全谷氨酰胺过敏的患病率为2.1% (95% CI， 1.6%至2.7%)，而2002年为1.2% (P = 0.007)， 1997年为0.6% （P < 0.001）。2008年儿童花生过敏患病率为1.4% (95% CI, 1.0% ~ 1.9%)， 2002年为0.8% （P =无统计学意义），1997年为0.4% （P < 0.0001）。儿童全氮过敏的患病率在调查期间显著增加（2008年为1.1%，2002年为0.5%，1997年为0.2%）。芝麻过敏发生率为0.1% （95% CI, 0.0% ~ 0.2%）。结论：虽然在比较调查时需要谨慎，但花生过敏，TN过敏，或两者兼有，仍有超过1%的美国人口（例如，1,300万受试者）报告，并且在过去十年中，在儿童中报告的人数似乎越来越多。芝麻过敏的报道要少得多。[J] .中华过敏症杂志，2010;25(5):326 - 326。
Background: Allergy to peanuts and tree nuts (TNs) is the leading cause of fatal allergic reactions in the United States, and the prevalence appears to be increasing.Objectives: We sought to determine the US prevalence of self-reported peanut, TN, and sesame allergy in 2008 and compare results with comparable surveys conducted in 1997 and 2002.Methods: A nationwide, cross-sectional, random telephone survey for peanut and TN allergy was conducted with a previously used questionnaire, with additional questions about sesame.Results: A total of 5,300 households (13,534 subjects) were surveyed (participation rate, 42% vs 52% in 2002 and 67% in 1997). Peanut allergy, TN allergy, or both was reported by 1.4% of subjects (95% Cl, 1.2% to 1.6%) compared with 1.2% in 2002 and 1.4% in 1997. For adults, the prevalence was 1.3% (95% CI, 1.1% to 1.6%), which was not significantly different from prior surveys. However, the prevalence of peanut or TN allergy for children younger than 18 years was 2.1% (95% CI, 1.6% to 2.7%) compared with 1.2% in 2002 (P = .007) and 0.6% in 1997 (P < .001). The prevalence of peanut allergy in children in 2008 was 1.4% (95% CI, 1.0% to 1.9%) compared with 0.8% in 2002 (P = not significant) and 0.4% in 1997 (P < .0001). The prevalence of childhood TN allergy increased significantly across the survey waves (1.1% in 2008, 0.5% in 2002, and 0.2% in 1997). Sesame allergy was reported by 0.1% (95% CI, 0.0% to 0.2%).Conclusions: Although caution is required in comparing surveys, peanut allergy, TN allergy, or both continue to be reported by more than 1% of the US population (eg, >3 million subjects) and appear to be increasingly reported among children over the past decade. Sesame allergy is reported much less commonly. (J Allergy Clin Immunol 2010;125:1322-6.)