On the possibilities of x-ray phase contrast microimaging by coherent high-energy synchrotron radiation
On the possibilities of x-ray phase contrast microimaging by coherent high-energy synchrotron radiation
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DOI：
10.1063/1.1146073
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发表时间：
1995-12-01
影响因子：
1.6
通讯作者：
Schelokov, I
中科院分区：
文献类型：
--
作者：
Snigirev, A;Snigireva, I;Schelokov, I
在ESRF发射的X射线束的相干特性允许观测到波前的非常微弱的扰动，从而产生相位对比。提出了一种简单的相衬成像实验装置，用于记录10-100微米、能量10-50keV、对比度达50%-100%的有机样品的全息像。讨论了相衬成像的原理，并从分辨率、灵敏度、几何要求和能量范围适用性等方面对该方法进行了理论估计。研究发现，对于碳基纤维，10keV对比度为2%的可检测尺寸为0.1微米，100keV为-1微米。结果表明，图像的精细干涉结构对样品的形状、密度变化和内部结构非常敏感。展望了相差显微镜、显微层析、全息、高能干涉等新的相干技术的实际应用和发展前景。(C)1995年美国物理研究所。
Coherent properties of the x-ray beam delivered at the ESRF allow the observation of very weak perturbations of the wave front, resulting in the phase contrast. A straightforward experimental setup for phase contrast imaging is proposed and used to record holographic images from organic samples of 10-100 mu m at energy 10-50 keV with the contrast up to 50%-100%. The theory of phase contrast imaging is considered and some theoretical estimations are made to reveal the performance of the proposed technique in terms of resolution, sensitivity, geometrical requirements, and energy range applicability. It is found that for carbon-based fibers a detectable size with 2% contrast is 0.1 mu m for 10 keV and -1 mu m for 100 keV. It is demonstrated that the fine interference structure of the image is very sensitive to the shape, density variation, and internal structure of the sample. Some prospects for the practical use and future development of the new coherent techniques such as phase contrast microscopy, microtomography, holography, and interferometry at high energies are also discussed. (C) 1995 American Institute of Physics.