A RHINOVIRUS OUTBREAK AMONG RESIDENTS OF A LONG-TERM-CARE FACILITY
A RHINOVIRUS OUTBREAK AMONG RESIDENTS OF A LONG-TERM-CARE FACILITY
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DOI：
10.7326/0003-4819-123-8-199510150-00004
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发表时间：
1995-10-15
影响因子：
39.2
通讯作者：
GRAVENSTEIN, S
中科院分区：
文献类型：
--
作者：
WALD, TG;SHULT, P;GRAVENSTEIN, S
目的：描述一个发生在养老院老年人中的鼻病毒爆发的流行病学和临床结果，设计：回顾性回顾医疗记录和护理监测报告，设置：一个685张床位的长期护理机构，为退伍军人及其配偶提供服务，患者：33名患者，鼻病毒培养，测量：咽喉和鼻咽病毒培养，呼吸道病毒培养。审查医疗记录，以确定潜在的疾病，呼吸道疾病的体征和症状，疾病的持续时间，并在患病期间的干预措施;和审查护理监督报告，以确定房间位置的病人。结果：1993年8月14日和9月2日之间，呼吸道疾病的数量增加。从67名患病居民的咽喉和鼻咽病毒培养; 33个培养产生鼻病毒，没有分离出其他呼吸道病毒。观察到鼻病毒感染者的地理聚集。在鼻病毒感染者中，100%有上呼吸道症状，34%有胃肠道症状，71%有全身症状，66%有下呼吸道症状（包括排痰性咳嗽），52%有肺部听诊新异常。鼻病毒感染慢性阻塞性肺疾病的17人有更严重的疾病：5（29%）需要糖皮质激素或支气管扩张剂治疗疾病相关的支气管痉挛; 2需要转移出设施; 1开发了一个放射学记录的浸润;和1死于呼吸衰竭。结论：鼻病毒可能会导致流行病，临床上重要的呼吸系统疾病的疗养院居民。很大一部分居民可能会生病，在患有潜在肺部疾病的人中，感染可能会很严重。
Objective: To describe the epidemiology of and clinical findings associated with a rhinovirus outbreak that occurred among institutionalized elderly persons.Design: Retrospective review of medical records and nursing surveillance reports.Setting: A 685-bed, long-term care facility for veterans and their spouses.Patients: 33 persons from whom rhinovirus was cultured.Measurements: Throat and nasopharyngeal virus culture; review of medical records to determine under-lying diseases, signs and symptoms of respiratory illness, illness duration, and interventions during illness; and review of nursing surveillance reports to determine room locations of ill persons.Results: Between 14 August and 2 September 1993, the number of respiratory illnesses increased. Throat and nasopharyngeal virus cultures were taken from 67 ill residents; 33 cultures yielded rhinovirus, and no other respiratory virus was isolated. Geographic clustering of persons infected with rhinovirus was observed. Of those persons with rhinovirus infections, 100% had upper respiratory symptoms, 34% had gastrointestinal symptoms, 71% had systemic symptoms, 66% had lower respiratory symptoms (including productive cough), and 52% had new abnormalities on lung auscultation. The 17 persons with rhinovirus infection who had chronic obstructive pulmonary disease had more severe illnesses: Five (29%) required glucocorticoid or bronchodilator therapy for illness-associated bronchospasm; 2 required transfer out of the facility; 1 developed a radiographically documented infiltrate; and 1 died of respiratory failure.Conclusions: Rhinovirus may cause epidemic, clinically important respiratory illness in nursing home residents. A large proportion of residents may become ill, and infection may be severe in persons with underlying lung disease.