Porous silicon-based scaffolds for tissue engineering and other biomedical applications
Porous silicon-based scaffolds for tissue engineering and other biomedical applications
复制标题
DOI：
10.1002/pssa.200461134
复制
发表时间：
2005-06-01
影响因子：
2
通讯作者：
Canham, LT
中科院分区：
文献类型：
--
作者：
Coffer, JL;Whitehead, MA;Canham, LT
本工作描述了基于生物活性中孔硅和生物可蚀性聚合物如聚己内酯（PCL）的组合的多孔复合材料的形成。讨论了一系列由盐浸和微乳液技术制备的复合材料的制备。特别注意在体外钙化测定的复合材料中的硅含量的影响进行了评估。对于每种系统，通过成纤维细胞培养试验明确评价细胞毒性和细胞增殖。(c)2005 WILEY-VCH Verlag GmbH & Co. KGaA，魏因海姆。
This work describes the formation of porous composite materials based on a combination of bioactive mesoporous silicon and bioerodible polymers such as poly-caprolactone (PCL). The fabrication of a range of composites prepared by both salt leaching and microemulsion techniques are discussed. Particular attention to the influence of Si content in the composite on in vitro calcification assays are assessed. For each system, cytotoxicity and cellular proliferation are explicitly evaluated through fibroblast cell culture assays. (c) 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.