Cu(I)-catalyzed stereospecific coupling reactions of enantioenriched α-stannylated benzyl carbamates and their application
Cu(I)-catalyzed stereospecific coupling reactions of enantioenriched α-stannylated benzyl carbamates and their application
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DOI：
10.1016/j.tet.2008.06.092
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发表时间：
2008-09-15
期刊：
影响因子：
2.1
通讯作者：
Hoppe, Dieter
中科院分区：
文献类型：
--
作者：
Lange, Heiko;Froehlich, Roland;Hoppe, Dieter
将富对映体的α-锡基苄基氨基甲酸酯用于以铜(I)为催化剂的高度立体定向偶联反应。以酸性氯化物和烯丙基溴为亲电偶联伙伴。该反应通过分子内环化反应合成了两个高对映体富集型吲哚和一个富对映体四氢呋喃。(C)2008爱思唯尔有限公司。保留所有权利。
Enantioenriched alpha-stannylated benzyl carbamates were used in highly stereospecific Coupling reactions employing Cu(I) as catalyzing transition metal. Acid chlorides and allyl bromide derivatives were used as electrophilic coupling partners. The reaction was applied in the synthesis of two highly enantioenriched indanoles and one enantioenriched tetraline via intramolecular cyclization reactions. (C) 2008 Elsevier Ltd. All rights reserved.