A pilot study of hereditary breast and ovarian knowledge among a multiethnic group of Hispanic women with a personal or family history of cancer.
A pilot study of hereditary breast and ovarian knowledge among a multiethnic group of Hispanic women with a personal or family history of cancer.
复制标题
一项针对具有癌症个人或家族史的多种族西班牙裔女性群体的遗传性乳腺癌和卵巢知识的试点研究。
DOI：
10.1089/gtmb.2009.0088
复制
发表时间：
2010
影响因子：
1.4
通讯作者：
Gwede,ClementK
中科院分区：
文献类型：
--
作者：
Vadaparampil,SusanT;Quinn,GwendolynP;Small,BrentJ;McIntyre,Jessica;Loi,ClaudiaAguado;Closser,Zuheily;Gwede,ClementK
PurposeTo检查有关遗传性乳腺癌和卵巢癌（HBOC）在墨西哥，波多黎各和古巴women.MethodsWomen（年龄范围，18-65岁）与乳腺癌或卵巢癌的个人或家族史的知识被招募到一个混合的方法研究，使用社区为基础的方法。53名女性参与了这项研究：16名墨西哥人，20名波多黎各人和17名古巴人。大多数女性（64.2%）出生在美国境外。所有问题都是用西班牙语或英语进行的面试。HBOC知识是使用国家人类基因组研究中心开发的11项仪器测量的。我们评估了知识的差异是否不同的西班牙裔subethnicity，人口统计学特征，医疗和文化适应的特点，使用一系列的单向方差分析。ResultsThe知识工具的正确反应的百分比范围从9.4%到73.6%（正确反应的中位数= 45%）。知识没有显着差异西班牙裔subethnicity（p= 0.51）。探索性分析显示，知识较低的妇女与个人病史的癌症（p= 0.03）。ConclusionOur研究提供了重要的信息与知识水平较低的相关特征和特定领域的HBOC在西班牙裔社区额外的教育可能是必要的。
PurposeTo examine knowledge about hereditary breast and ovarian cancer (HBOC) among Mexican, Puerto Rican, and Cuban women.MethodsWomen (age range, 18–65 years) with a personal or family history of breast or ovarian cancer were recruited to a mixed methods study using community-based approaches. Fifty-three women participated in the study: 16 Mexicans, 20 Puerto Ricans, and 17 Cubans. The majority of women (64.2%) were born outside the United States. All questions were interviewer administered in Spanish or English. HBOC knowledge was measured using an 11-item instrument developed by the National Center for Human Genome Research. We evaluated whether differences in knowledge varied as a function of Hispanic subethnicity, demographic characteristics, and medical and acculturation characteristics using a series of one-way analysis of variances.ResultsThe percentage of correct responses on the knowledge instrument ranged from 9.4% to 73.6% (median number of correct responses = 45%). Knowledge did not significantly differ by Hispanic subethnicity (p= 0.51). Exploratory analysis revealed lower knowledge in women with a personal history of cancer (p= 0.03).ConclusionOur study provides important information about characteristics associated with lower levels of knowledge and specific areas related to HBOC where additional education may be warranted in the Hispanic community.