Isolation and molecular characterization of Fikirini rhabdovirus, a novel virus from a Kenyan bat

Isolation and molecular characterization of Fikirini rhabdovirus, a novel virus from a Kenyan bat
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DOI:
10.1099/vir.0.053983-0
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发表时间:
2013-11-01
影响因子:
3.8
通讯作者:
Miller, Barry R.
Miller, Barry R.
中科院分区:
医学3区
文献类型:
--
作者:
Kading, Rebekah C.;Gilbert, Amy T.;Miller, Barry R.

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近几十年来,人畜共患和病媒传播的病原体构成了新出现的人类感染的重要组成部分,蝙蝠越来越被认为是许多这些疾病病原体的宿主。为了确定与蝙蝠相关的新病原体,我们筛选了在肯尼亚收集的蝙蝠组织。通过对来自感染细胞培养物上清液的病毒核酸制备物进行下一代测序来鉴定病毒分离株并进行表征。在这里,我们报告的Fikirini弹状病毒,一种新的弹状病毒分离的蝙蝠,蹄蝠,捕获沿着肯尼亚海岸。
Zoonotic and vector-borne pathogens have comprised a significant component of emerging human infections in recent decades, and bats are increasingly recognized as reservoirs for many of these disease agents. To identify novel pathogens associated with bats, we screened tissues of bats collected in Kenya. Virus isolates were identified by next generation sequencing of viral nucleic acid preparations from the infected cell culture supernatant and characterized. Here we report the identification of Fikirini rhabdovirus, a novel rhabdovirus isolated from a bat, Hipposideros vittatus, captured along the Kenyan coast.