IMMUNOCYTOCHEMICAL LOCALIZATION OF ACTH PERIKARYA IN NUCLEUS TRACTUS SOLITARIUS - EVIDENCE FOR A 2ND OPIOCORTIN NEURONAL SYSTEM
IMMUNOCYTOCHEMICAL LOCALIZATION OF ACTH PERIKARYA IN NUCLEUS TRACTUS SOLITARIUS - EVIDENCE FOR A 2ND OPIOCORTIN NEURONAL SYSTEM
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DOI：
10.1016/0304-3940(83)90372-5
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发表时间：
1983-01-01
影响因子：
2.5
通讯作者：
BENNETTCLARKE, C
中科院分区：
文献类型：
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作者：
JOSEPH, SA;PILCHER, WH;BENNETTCLARKE, C
用免疫细胞化学方法研究了ACTH-阿片皮质素在秋水仙碱处理的大鼠延髓内的分布。孤束核尾侧区有丰富的ACTH免疫反应神经元胞体和纤维，特别是在连合部。这些阿片皮质素神经元在孤束核中的位置为这些肽在心血管功能中的作用提供了额外的证据。
Immunocytochemical localization of ACTH-opiocortin perikarya was demonstrated in the medulla of colchicine-treated rat. Neuronal cell bodies and fibers containing ACTH-immunoreactivity were abundant in the caudal region of the nucleus tractus solitarius, specifically within pars commisuralis. Location of these opiocortin neurons within the nucleuus tractus solitarius provides additional evidence for a role of these peptides in cardiovascular functions.