LUNG-MECHANICS IN CONGENITAL HEART-DISEASE WITH INCREASED AND DECREASED PULMONARY BLOOD-FLOW
LUNG-MECHANICS IN CONGENITAL HEART-DISEASE WITH INCREASED AND DECREASED PULMONARY BLOOD-FLOW
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DOI：
10.1016/s0022-3476(77)80628-8
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发表时间：
1977-01-01
影响因子：
5.1
通讯作者：
GARCIA, O
中科院分区：
文献类型：
--
作者：
BANCALARI, E;JESSE, MJ;GARCIA, O
对25例患儿进行心导管置管后24 h内呼吸频率、潮气量（VT）、肺动态顺应性（CL）、功能剩余容量（FRC）、肺阻力的测定，其中12例患儿肺血流量（PBF）增加，13例患儿肺血流量（PBF）减少。两组患者在VT和FRC方面无差异。PBF增高的婴儿呼吸频率和肺阻力增高。PBF升高（4.9 ml/cm H2O）的患儿肺顺应性明显低于PBF降低（8.9 ml/cm H2O）的患儿（P < 0.01）。PBF升高的婴儿CL降低与平均肺动脉压显著相关（r = 0.798）。CL与左房压或左至右分流大小无相关性。在PBF升高和PAP（肺动脉压）正常的患者中，依从性正常，提示PAP而非PBF是影响心内左向右分流患者CL的主要因素。
Respiratory rate, tidal volume [VT], dynamic lung compliance [CL], functional residual capacity [FRC], and pulmonary resistance were measured within 24 h of cardiac catheterization in 25 infants, 12 of whom had increased pulmonary blood flow [PBF] and 13 of whom had decreased PBF. There were no differences in the 2 groups of patients with respect to VT and FRC. Respiratory rate and pulmonary resistance were higher in infants with increased PBF. Lung compliance was significantly lower in infants with increased PBF (4.9 ml/cm H2O) than in those with decreased PBF (8.9 ml/cm H2O) (P < 0.01). The decrease in CL in infants with increased PBF significantly correlated with mean pulmonary artery pressure (r = 0.798). No correlation was found between CL and left atrial pressure or magnitude of the left-to-right shunt. Compliance was normal in patients with increased PBF and normal PAP [pulmonary artery pressure], suggesting that PAP and not PBF is the primary factor that affects CL in patients with intracardiac left-to-right shunts.