Has2 deficiency enhances OVA-induced airway inflammation and hyperresponsiveness in mice

Has2 deficiency enhances OVA-induced airway inflammation and hyperresponsiveness in mice
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Has2 缺陷会增强 OVA 诱导的小鼠气道炎症和高反应性

DOI:
10.1111/all.14715
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发表时间:
2021
期刊:
影响因子:
12.4
通讯作者:
Nobuyuki Hizawa
Nobuyuki Hizawa
中科院分区:
医学1区
文献类型:
--
作者:
Yoshiya Tsunoda;Mingma Thsering Sherpa;Takumi Kiwamoto;Masashi Matsuyama;Hajime Osawa;Hirofumi Sakurai;Shigen Hayashi;Yosuke Matsuno;Yuko Morishima;Yukio Ishii;Nobuyuki Hizawa

文献摘要

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综上所述,我们证明了I - Has2 I表达的衰减可增强ova诱导的小鼠气道炎症和AHR,并减弱CD44和tgf信号。(右)使用wt -生理盐水、Has2+/-生理盐水、WT-OVA和Has2+/- OVA对小鼠肺组织进行HA大小分析。【摘自文章】过敏症的版权是Wiley-Blackwell的财产,未经版权所有者的明确书面许可,其内容不得复制或通过电子邮件发送到多个网站或发布到listserv。但是,用户可以打印、下载或通过电子邮件发送文章供个人使用。这篇摘要可以删节。对副本的准确性不作任何保证。用户应参考资料的原始出版版本以获取完整摘要。版权适用于所有摘要。
Has2 deficiency enhances OVA-induced airway inflammation and hyperresponsiveness in mice In conclusion, we demonstrated that the attenuation of I Has2 i expression enhances OVA-induced airway inflammation and AHR and attenuates CD44 and TGF-signaling in mice.(right) HA size analysis using WT-saline, Has2+/--saline, WT-OVA, and Has2+/--OVA mouse lung tissue.[Extracted from the article]Copyright of Allergy is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. Copyright applies to all Abstracts.