Clinical, psychological, and sensory characteristics associated with headache attributed to temporomandibular disorder in people with chronic myogenous temporomandibular disorder and primary headaches.
Clinical, psychological, and sensory characteristics associated with headache attributed to temporomandibular disorder in people with chronic myogenous temporomandibular disorder and primary headaches.
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DOI：
10.1186/s10194-021-01255-1
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发表时间：
2021-05-22
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影响因子：
--
通讯作者：
Slade GD
中科院分区：
文献类型：
--
作者：
Tchivileva IE;Ohrbach R;Fillingim RB;Lin FC;Lim PF;Arbes SJ Jr;Slade GD
颞下颌关节紊乱病（HATMD）引起的头痛是一种继发性头痛，可能具有导致与原发性头痛（即紧张型（TTH）或偏头痛）诊断重叠的特征。这项对慢性肌源性TMD和原发性头痛患者的横断面研究评估了与HATMD相关的特征。从成人临床试验中，基线数据来自根据TMD诊断标准（DC/TMD）诊断为TMD肌痛和根据头痛疾病国际分类第3版诊断为TTH或偏头痛的子集。HATMD是根据DC/TMD进行分类的。调查问卷和检查评估了面部疼痛、头痛、一般健康状况、心理困扰和实验性疼痛敏感性的42个特征。单变量回归模型量化了每个特征与HATMD（存在与不存在）、头痛类型（TTH与偏头痛）的关联，以及析因设计中的相互作用。多变量Lasso回归确定了HATMD最重要的预测因子。在185名参与者中，114名（61.6%）患有HATMD，而TTH（n = 98，53.0%）和偏头痛（n = 87，47.0%）的人数相似。偏头痛患者（61/87 = 70.1%）比TTH患者（53/98 = 54.1%;比值比= 2.0; 95%CL = 1.1，3.7）更容易发生HATMD。在单变量分析中，与HATMD相关的特征包括无痛的下颌张开和检查诱发的咀嚼肌和颞下颌关节（TMJ）疼痛以及头痛的频率和影响，但不包括面部疼痛的频率或影响。血压降低而不是心理或感觉特征与HATMD相关。TTH组和偏头痛组的面部疼痛、头痛、一般健康状况和心理困扰的多重特征不同。观察到很少的相互作用，表明大多数特征与HATMD的关联在TTH和偏头痛组中是一致的。套索模型确定头痛频率和检查诱发的肌肉疼痛是HATMD最重要的预测因子。HATMD在患有慢性肌源性TMD和头痛的患者中非常普遍，并且通常表现为偏头痛。与原发性头痛相比，HATMD与更高的头痛频率和检查诱发的咀嚼肌疼痛相关，但令人惊讶的是，面部疼痛，一般健康状况和心理困扰的措施很少。更好地了解HATMD对于制定有针对性的管理战略是必要的。SOPPRANO; NCT 02437383。2015年5月7日注册。在线版本包含补充材料，可通过10.1186/s10194-021-01255-1获得。
Headache attributed to Temporomandibular Disorder (HATMD) is a secondary headache that may have features resulting in diagnostic overlap with primary headaches, namely, tension-type (TTH) or migraine. This cross-sectional study of people with both chronic myogenous TMD and primary headaches evaluated characteristics associated with HATMD. From a clinical trial of adults, baseline data were used from a subset with diagnoses of both TMD myalgia according to the Diagnostic Criteria for TMD (DC/TMD) and TTH or migraine according to the International Classification of Headache Disorders, 3rd edition. HATMD was classified based on the DC/TMD. Questionnaires and examinations evaluated 42 characteristics of facial pain, headache, general health, psychological distress, and experimental pain sensitivity. Univariate regression models quantified the associations of each characteristic with HATMD (present versus absent), headache type (TTH versus migraine), and their interaction in a factorial design. Multivariable lasso regression identified the most important predictors of HATMD. Of 185 participants, 114 (61.6%) had HATMD, while the numbers with TTH (n = 98, 53.0%) and migraine (n = 87, 47.0%) were similar. HATMD was more likely among migraineurs (61/87 = 70.1%) than participants with TTH (53/98 = 54.1%; odds ratio = 2.0; 95%CL = 1.1, 3.7). In univariate analyses, characteristics associated with HATMD included pain-free jaw opening and examination-evoked pain in masticatory muscles and temporomandibular joints (TMJ) as well as frequency and impact of headache, but not frequency or impact of facial pain. Lowered blood pressure but not psychological or sensory characteristics was associated with HATMD. Multiple characteristics of facial pain, headache, general health, and psychological distress differed between TTH or migraine groups. Few interactions were observed, demonstrating that most characteristics’ associations with HATMD were consistent in TTH and migraine groups. The lasso model identified headache frequency and examination-evoked muscle pain as the most important predictors of HATMD. HATMD is highly prevalent among patients with chronic myogenous TMD and headaches and often presents as migraine. In contrast to primary headaches, HATMD is associated with higher headache frequency and examination-evoked masticatory muscle pain, but with surprisingly few measures of facial pain, general health, and psychological distress. A better understanding of HATMD is necessary for developing targeted strategies for its management. SOPPRANO; NCT02437383. Registered May 7, 2015. The online version contains supplementary material available at 10.1186/s10194-021-01255-1.
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影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
DOI：
10.14219/jada.archive.2006.0385
发表时间：
2006-09-01
影响因子：
3.9
作者：
Mitrirattanakul, Somsak;Merrill, Robert L.
通讯作者：
Merrill, Robert L.
DOI：
10.1186/s10194-016-0649-2
发表时间：
2016
期刊：
The journal of headache and pain
影响因子：
--
作者：
Lampl C;Thomas H;Tassorelli C;Katsarava Z;Laínez JM;Lantéri-Minet M;Rastenyte D;Ruiz de la Torre E;Stovner LJ;Andrée C;Steiner TJ
通讯作者：
Steiner TJ
DOI：
10.1111/j.1600-0528.2007.00397.x
发表时间：
2008-06-01
影响因子：
2.3
作者：
Ohrbach, Richard;Granger, Carl;Dworkin, Samuel
通讯作者：
Dworkin, Samuel
DOI：
10.1007/978-3-319-19425-7_13
发表时间：
2015-01-01
期刊：
REGRESSION MODELING STRATEGIES: WITH APPLICATIONS TO LINEAR MODELS, LOGISTIC AND ORDINAL REGRESSION, AND SURVIVAL ANALYSIS, 2ND EDITION
影响因子：
--
作者：
Harrell, Frank E., Jr.
通讯作者：
Harrell, Frank E., Jr.