Neurocognitive outcomes and recovery after pediatric TBI: meta-analytic review of the literature.

Neurocognitive outcomes and recovery after pediatric TBI: meta-analytic review of the literature.
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DOI:
10.1037/a0015268
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发表时间:
2009-05
期刊:
影响因子:
2.4
通讯作者:
Asarnow, Robert
Asarnow, Robert
中科院分区:
心理学3区
文献类型:
--
作者:
Babikian, Talin;Asarnow, Robert

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创伤性脑损伤(TBI)仍然是儿童死亡和残疾的主要原因之一。尽管关于神经认知结果的文献相对丰富,但研究在根据几个调节变量(包括受伤年龄、受伤严重程度和受伤后时间)对受试者进行分组的方法上存在显著差异,这使得很难将数据合并和总结以进行比较。进一步使这一努力复杂化的是用于记录关键神经认知领域功能结果的广泛测量。在这篇荟萃分析综述中,根据14个关键神经认知领域的三种不同的损伤严重程度和损伤后时间分组,总结了28篇符合纳入标准的出版物(1988 - 2007)。计算效应大小以反映上述组在病例对照和病例研究中的差异程度,以及基于纵向研究的恢复问题。据我们所知,这是首次发表的关于小儿脑外伤后神经认知结果的文献定量总结。讨论了当前文献的局限性以及对未来研究的建议。
Traumatic Brain Injury (TBI) continues to be one of the leading causes of death and disability in the pediatric population. Although the literature on neurocognitive outcomes is relatively rich, studies vary significantly in the methods used to group subjects on several moderating variables, including age at injury, injury severity, and time since injury, making it difficult to combine and summarize the data for comparison. Further complicating this effort is the wide range of measures used to document functional outcomes in key neurocognitive domains. In this meta-analytic review, 28 publications (1988 to 2007) that met inclusion criteria were summarized based on three distinct injury severity and time post injury groups for 14 key neurocognitive domains. Effect sizes were calculated to reflect the extent to which the above groups differed in case-control and case-case studies, as well as address recovery based on longitudinal studies. To the best of our knowledge, this is the first published quantitative summary of the literature on neurocognitive outcomes after pediatric TBI. Limitations of the current state of the literature as well as recommendations for future studies are discussed.
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