Effect of kosmotropicity of ionic liquids on the enzyme stability in aqueous solutions.
Effect of kosmotropicity of ionic liquids on the enzyme stability in aqueous solutions.
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DOI：
10.1016/j.bioorg.2005.10.004
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发表时间：
2006-02
影响因子：
5.1
通讯作者：
Hua Zhao;Olarongbe Olubajo;Zhiyan Song;Artez L Sims;Terra E Person;Rasheed A Lawal;Ladena A Holley
中科院分区：
文献类型：
--
作者：
Hua Zhao;Olarongbe Olubajo;Zhiyan Song;Artez L Sims;Terra E Person;Rasheed A Lawal;Ladena A Holley
研究了几种吡啶类和咪唑类离子液体对蛋白酶稳定性的影响。在一般情况下，酶被发现在低浓度的亲水性离子液体相当活跃。在水环境中，该酶被亲液阴离子（如CF 3COO-和CH 3COO-）和离液阳离子（如[BuPy]+和[EMIM]+）稳定，但被离液阴离子（如甲苯磺酸根和BF 4-）和亲液阳离子（如[BMIM]+）去稳定。
This paper examined the effect of several pyridinium and imidazolium-based ionic liquids (ILs) on the protease stability in aqueous solutions. In general, the enzyme was found quite active at low concentrations of hydrophilic ILs. In aqueous environment, the enzyme was stabilized by the kosmotropic anions (such as CF3COO−and CH3COO−) and chaotropic cations (such as [BuPy]+and [EMIM]+), but was destabilized by chaotropic anions (such as tosylate and BF4−) and kosmotropic cations (such as [BMIM]+).