Biologically different subgroups of invasive ductal carcinoma of the pancreas: Dpc4 status according to the ratio of intraductal carcinoma components
Biologically different subgroups of invasive ductal carcinoma of the pancreas: Dpc4 status according to the ratio of intraductal carcinoma components
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DOI：
10.1158/1078-0432.ccr-03-0120
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发表时间：
2004-06-01
影响因子：
11.5
通讯作者：
Ochiai, A
中科院分区：
文献类型：
--
作者：
Takahashi, H;Oda, T;Ochiai, A
目的：在胰腺浸润性导管癌（IDCP）中，有一个形态学特征的亚组，伴有丰富的导管内癌成分（ICC）。实验设计：将总共43个IDCP再分为两组：（a）富含ICC的IDCP（ICC面积占整个肿瘤面积的大于或等于10%）;和（B）ICC贫乏的IDCP（ICC面积占整个肿瘤面积的大于或等于10%）。
Purpose: Among invasive ductal carcinomas of the pancreas (IDCP), there is a morphologically characteristic subgroup accompanied by abundant intraductal carcinoma components (ICCs). With the aim of determining whether ICC-rich IDCP are biologically different from ICC-poor IDCP, the expression status of Dpc4 protein was analyzed.Experimental Design: A total of 43 IDCP was subdivided into two groups: (a) ICC-rich IDCP (ICCs area occupies greater than or equal to10% of the entire tumorous area); and (b) ICC-poor IDCP (with