The priming effect of alcohol pre-load on attentional bias to alcohol-related stimuli
The priming effect of alcohol pre-load on attentional bias to alcohol-related stimuli
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DOI：
10.1007/s00213-004-1906-7
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发表时间：
2004-11-01
影响因子：
3.4
通讯作者：
Townshend, JM
中科院分区：
文献类型：
--
作者：
Duka, T;Townshend, JM
背景：以往的研究表明，非依赖性社交饮酒者对酒精相关刺激存在注意偏向。本研究的目的是调查是否注意偏向酒精相关的刺激后，启动与两个剂量的酒精（0.3或0.6克/公斤）或安慰剂之一会增加。方法：使用问卷测量酒精使用、情绪状态、对酒精的渴望和酒精结果预期。使用点探针检测任务和改良Stroop任务评估注意偏差。结果：情绪评分显示酒精预负荷后积极情绪的剂量依赖性增加。在点探测任务中，所有受试者都表现出对酒精相关刺激的注意偏向，而不是中性文具相关项目，尽管注意偏向仅在低酒精剂量下显着为正。此外，高酒精剂量下的注意偏向与酒精使用问卷得分呈负相关。在Stroop任务中，发现酒精的剂量相关效应，与酒精相关的词，在高酒精剂量下的错误更多。结论：这些数据支持来自药物成瘾的激励学习理论的观点。此外，这些数据表明，酒精暴露史可能会影响酒精预负荷的注意偏向启动效应。
Background: Previous research has shown attentional bias toward alcohol-related stimuli in non-dependent social drinkers. The aim of this study was to investigate whether attentional bias towards alcohol-related stimuli would increase after priming with either one of two doses of alcohol (0.3 or 0.6 g/kg) or placebo. Methods: Questionnaires were used to measure alcohol use, mood states, craving for alcohol and alcohol outcome expectancies. Attentional bias was assessed using a dot-probe detection task and a modified Stroop task. Results: Mood ratings showed dose dependent increases in positive mood after the alcohol pre-load. In the dot-probe task, all subjects showed an attentional bias towards the alcohol-related stimuli over neutral stationery-related items, although the attentional bias was significantly positive only at the low alcohol dose. In addition, a negative correlation was found between the attentional bias under the high alcohol dose and the alcohol use questionnaire score. In the Stroop task, a dose related effect of alcohol was found, with subjects making more errors for alcohol-related words under the high alcohol dose. Conclusions: These data support ideas derived from the incentive learning theories of drug addiction. Furthermore, these data suggest that history of alcohol exposure may influence the priming effects of an alcohol pre-load on attentional bias.