Neutralizing antibodies in human serum after influenza A - The lack of strain specificity in the immunological response

Neutralizing antibodies in human serum after influenza A - The lack of strain specificity in the immunological response
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DOI:
10.1084/jem.74.5.433
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发表时间:
1941-11-01
影响因子:
15.3
通讯作者:
Rickard, ER
Rickard, ER
中科院分区:
医学1区
文献类型:
--
作者:
Horsfall, FL Jr;Rickard, ER

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越来越多的担忧。在甲型流感发生后,人类血清中出现的抗甲型流感病毒中和抗体的比例并不区分该病毒或猪流感病毒的抗原性不同毒株,但似乎对这些药物具有相同的反应性。随着时间的推移,抗体水平的下降也与用来测量它的病毒株无关。
The increased concs. of neutralizing antibodies against influenza A virus in human serum which occur after influenza A do not differentiate between antigenically different strains of this virus or swine influenza virus but instead appear to possess equal reactivity against these agents. The decrease in antibody levels which occurs with time is also independent of the strain of virus used to measure it.