Screening for duct-dependant congenital heart disease with pulse oximetry: a critical evaluation of strategies to maximize sensitivity.
Screening for duct-dependant congenital heart disease with pulse oximetry: a critical evaluation of strategies to maximize sensitivity.
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DOI：
10.1080/08035250510039900
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发表时间：
2005-11-01
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影响因子：
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通讯作者：
Ostman-Smith, Ingegerd
中科院分区：
文献类型：
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作者：
de Wahl Granelli, Anne;Mellander, Mats;Ostman-Smith, Ingegerd
目的：评价出院前应用脉搏血氧仪检测导管依赖性先天性心脏病的可行性。设计：病例对照研究。地点：瑞典的一个儿科心脏外科超区域转诊中心。患者：200名超声心动图检查正常的正常足月新生儿（中位年龄1.0天）和66名患有重症先天性心脏病的婴儿（CCHD;中位年龄3天）。使用新一代脉搏血氧仪（NGoxi）和传统技术血氧仪（CToxi）在右手和一只脚上进行脉搏血氧测定。使用NGoxi时，正常新生儿的中位导管后饱和度为99%（范围94-100%）;观察者内变异性的平均差异为0%（SD 1.3%），观察者间变异性为0%（SD 1.5%）。与NGoxi相比，CToxi在正常新生儿中记录的导管后值低于95%的比例显著更高（41%对1%）（p
AIM: To evaluate the feasibility of detecting duct-dependent congenital heart disease before hospital discharge by using pulse oximetry.DESIGN: Case-control study.SETTING: A supra-regional referral centre for paediatric cardiac surgery in Sweden.PATIENTS: 200 normal term newborns with echocardiographically normal hearts (median age 1.0 d) and 66 infants with critical congenital heart disease (CCHD; median age 3 d).METHODS: Pulse oximetry was performed in the right hand and one foot using a new-generation pulse oximeter (NGoxi) and a conventional-technology oximeter (CToxi).RESULTS: With the NGoxi, normal newborns showed a median postductal saturation of 99% (range 94-100%); intra-observer variability showed a mean difference of 0% (SD 1.3%), and inter-observer variability was 0% (SD 1.5%). The CToxi recorded a significantly greater proportion of postductal values below 95% (41% vs 1%) in the normal newborns compared with NGoxi (p