Lineage selection leads to evolvability at large population sizes
Lineage selection leads to evolvability at large population sizes
复制标题
谱系选择导致大种群规模的进化
DOI：
10.7551/ecal_a_070
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发表时间：
2017
影响因子：
4.7
通讯作者：
Chrisantha Fernando
中科院分区：
文献类型：
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作者：
N. Virgo;E. Agmon;Chrisantha Fernando
进化的生物机制本身也可能受到自然选择的影响。已经提出了几种可以实现这一点的机制。在这里，我们认为，其中之一的谱系选择成为一个强大的选择力时，固定在人口的时间尺度是可比的适应的时间尺度。这意味着，任何减缓固定的因素都会增强谱系选择;特别是，我们预计，当种群非常大且空间扩散有限时，它的影响会很强。为了证明这一点，我们构建了一个简单的模型，空间结构的人口在一个固定的，但无限的，健身景观。这一景观由一条平坦的、可演化的道路组成，周围是崎岖的当地山峰。我们的模型表现出非常强的依赖于人口规模：随着其规模的增加，人口沿着平滑的路径发展，避免局部峰值，指数更长的时间。这些结果表明，选择的进化性mig…
The biological machinery of evolution can itself be subject to natural selection. Several mechanisms have been proposed through which this can happen. Here we argue that one of these—lineage selection—becomes a strong selective force when the time scale of fixation in the population is comparable to the time scale of adaptation. This implies that lineage selection will be enhanced by anything that slows down fixation; in particular, we expect its effects to be strong when populations are very large and when spatial diffusion is limited. To demonstrate this we construct a simple model of a spatially structured population evolving on a fixed, but infinite, fitness landscape. This landscape consists of a smooth, evolvable path surrounded by rugged local peaks. Our model exhibits an extremely strong dependence on population size: as its size is increased the population evolves along the smooth path, avoiding local peaks, for exponentially longer times. These results suggest that selection for evolvability mig...