Information theory, evolutionary innovations and evolvability

Information theory, evolutionary innovations and evolvability
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信息论、进化创新和可进化性

DOI:
10.1098/rstb.2016.0416
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发表时间:
2017
期刊:
Philosophical Transactions of the Royal Society B: Biological Sciences
影响因子:
--
通讯作者:
A. Wagner
A. Wagner
中科院分区:
--
文献类型:
--
作者:
A. Wagner

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“发现”进化适应或创新有多困难?我在此建议,信息论与高通量 DNA 测序相结合,可以通过量化新表型的信息内容来帮助回答这个问题。我应用这个框架来计算与新基因调控和使用新碳源的能力相关的表型信息。该框架还可以帮助量化 DNA 重复如何影响进化性、估计表型的复杂性并阐明达尔文进化论中“进步”的含义。本文是“从细胞到社会创新的过程与模式”主题的一部分。
How difficult is it to ‘discover’ an evolutionary adaptation or innovation? I here suggest that information theory, in combination with high-throughput DNA sequencing, can help answer this question by quantifying a new phenotype's information content. I apply this framework to compute the phenotypic information associated with novel gene regulation and with the ability to use novel carbon sources. The framework can also help quantify how DNA duplications affect evolvability, estimate the complexity of phenotypes and clarify the meaning of ‘progress’ in Darwinian evolution. This article is part of the themed issue ‘Process and pattern in innovations from cells to societies’.
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