Usefulness of the calculated apparent diffusion coefficient value in the differential diagnosis of retroperitoneal masses
Usefulness of the calculated apparent diffusion coefficient value in the differential diagnosis of retroperitoneal masses
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DOI：
10.1002/jmri.20149
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发表时间：
2004-10-01
影响因子：
4.4
通讯作者：
Honda, H
中科院分区：
文献类型：
--
作者：
Nakayama, T;Yoshimitsu, K;Honda, H
目的：为了阐明从回波平面扩散加权（EPDW）MR图像计算的表观扩散系数（ADC）值是否有助于腹膜后肿块的鉴别诊断，材料和方法：在50例已知腹膜后肿块的患者中，使用0-1100秒/mm（2）的b因子进行EPDW图像。这些病变的最终组织学诊断如下：12例恶性淋巴瘤，4例其他恶性间叶肿瘤，25例恶性上皮肿瘤，7例良性间叶肿瘤和2例非肿瘤性病变。ADC值获得的固体部分的病变被用来代表每一个病变，和值的组织学groups.Results：ADC值分别为12恶性淋巴瘤，4个其他间叶肿瘤，7良性间叶肿瘤，和两个非肿瘤性病变如下：0.66 +/- 0.26、1.26 +/- 0.50、0.90 +/- 0.20、1.87 +/- 0.48、1.32 +/- 0.20 x 10（-3）mm（2）/秒。恶性淋巴瘤的ADC值明显低于其他恶性间叶性病变，也低于良性病变。恶性上皮性肿瘤的ADC值低于良性间叶性肿瘤。良、恶性病变的ADC值分别为0.94 ± 0.30和1.75 ± 0.49 × 10 - 3 mm 2/s，两者差异有统计学意义。结论：EPDW图像ADC值可为腹膜后肿块的鉴别诊断提供有用的信息。
Purpose: To elucidate whether or not the apparent diffusion coefficient (ADC) values calculated from echo-planar diffusion-weighted (EPDW) MR images are useful in the differential diagnosis of retroperitoneal masses.Materials and Methods: In 50 patients with known retroperitoneal masses, EPDW images were performed with b-factors of 0-1100 seconds/mm(2). The final histologic diagnoses of these lesions were as follows: 12 malignant lymphomas, four other malignant mesenchymal neoplasms, 25 malignant epithelial neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions. The ADC values obtained for the solid portion of the lesions were used to represent each lesion, and the values of the histologic groups were compared.Results: The respective value of ADC for 12 malignant lymphomas, four other mesenchymal neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions were as follows: 0.66 +/- 0.26, 1.26 +/- 0.50, 0.90 +/- 0.20, 1.87 +/- 0.48, 1.32 +/- 0.20 x 10(-3) mm(2)/second. The ADC value of the malignant lymphoma was significantly lower than that of the other malignant mesenchymal lesions, and was also lower than the ADC of the benign lesions. The ADC value of the malignant epithelial neoplasms was lower than that of the benign mesenchymal tumors. The ADC values of the malignant and benign lesions were 0.94 +/- 0.30 and 1.75 +/- 0.49 x 10(-3) mm(2)/second, respectively, which also demonstrated a significant difference.Conclusion: ADC values calculated from EPDW MR images may provide useful information in the differential diagnosis of retroperitoneal masses.