Clinical review 46: Clinical utility of inhibin measurements.

Clinical review 46: Clinical utility of inhibin measurements.
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临床回顾 46:抑制素测量的临床效用。

DOI:
10.1210/jcem.76.6.8501140
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发表时间:
1993
期刊:
The Journal of clinical endocrinology and metabolism
影响因子:
--
通讯作者:
H. Burger
H. Burger
中科院分区:
--
文献类型:
--
作者:
H. Burger

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在未来几年内,针对各种形式的循环性腺肽的新的特异性检测方法(可能基于双位点检测技术)可能会出现,这反过来将开辟一系列潜在的临床应用,特别是在男科、排卵障碍的管理、特别是卵巢和其他恶性肿瘤方面。目前的抑制素检测已经被证明在卵巢癌的治疗中有很大的价值。最近关于抑制素亚基和二聚体激活素存在于人肾上腺的研究也提出了抑制素和激活素的测量可能最终适用于肾上腺疾病的研究的可能性。
New and specific assays, probably based on two-site assay technology, for various forms of circulating gonadal peptides are likely to be available within the next few years and these in turn should open up a range of potential clinical applications, particularly in andrology, management of ovulatory disorders, and especially ovarian and perhaps other malignancies. Current inhibin assays are already proving to be of great value in ovarian cancer management. The recent demonstration that inhibin subunits and dimeric activin are present in the human adrenal also raises the possibility that measurement of inhibin and activin may ultimately be applicable to the study of adrenal disorders.