Comparative analysis of the brain transcriptome in a hyper-aggressive fruit fly, Drosophila prolongata
Comparative analysis of the brain transcriptome in a hyper-aggressive fruit fly, Drosophila prolongata
复制标题
DOI：
10.1016/j.ibmb.2017.01.006
复制
发表时间：
2017-03-01
影响因子：
3.8
通讯作者：
Matsuo, Takashi
中科院分区：
文献类型：
--
作者：
Kudo, Ayumi;Shigenobu, Shuji;Matsuo, Takashi
攻击性行为在许多动物中都可以观察到，但其强度因物种而异。在遗传学模式动物黑腹果蝇（Drosophila melanogaster）中，攻击性行为的遗传基础已被深入研究，包括转录组分析以鉴定其表达水平与攻击性的种内变异相关的基因。然而，这些基因是否也参与了不同物种之间攻击性的进化还没有被研究。在这项研究中，我们在果蝇的大脑中进行了从头转录组分析，以确定与侵略性进化相关的基因。男性D.与近缘种相比，黑腹果蝇具有高度的攻击性。通过比较脑组织转录组发现了21个差异表达基因。prolongata.它们与D.黑腹果蝇，这表明参与侵略性进化的基因独立于与果蝇侵略性种内变异相关的基因。虽然雌性D.在本研究中鉴定的21个基因的表达水平在性别之间比在物种之间更相似。(C)2017爱思唯尔有限公司版权所有
Aggressive behavior is observed in many animals, but its intensity differs between species. In a model animal of genetics, Drosophila melanogaster, genetic basis of aggressive behavior has been studied intensively, including transcriptome analyses to identify genes whose expression level was associated with intra-species variation in aggressiveness. However, whether these genes are also involved in the evolution of aggressiveness among different species has not been examined. In this study, we performed de novo transcriptome analysis in the brain of Drosophila prolongata to identify genes associated with the evolution of aggressiveness. Males of D. prolongata were hyper-aggressive compared with closely related species. Comparison of the brain transcriptomes identified 21 differentially expressed genes in males of D. prolongata. They did not overlap with the list of aggression-related genes identified in D. melanogaster, suggesting that genes involved in the evolution of aggressiveness were independent of those associated with the intra-species variation in aggressiveness in Drosophila. Although females of D. prolongata were not aggressive as the males, expression levels of the 21 genes identified in this study were more similar between sexes than between species. (C) 2017 Elsevier Ltd. All rights reserved.