Medical care contact for infertility and related medication use during pregnancy - a European, cross-sectional web-based study.
Medical care contact for infertility and related medication use during pregnancy - a European, cross-sectional web-based study.
复制标题
DOI：
10.5324/nje.v29i1-2.4051
复制
发表时间：
2021-01-01
影响因子：
--
通讯作者：
Lupattelli, Angela
中科院分区：
文献类型：
--
作者：
Ilic, Miljana;Nordeng, Hedvig;Lupattelli, Angela
目的：该研究的目的有两个：（一）确定欧洲国家不孕症医疗护理接触的流行率;（二）绘制因不孕症寻求医疗护理的妇女在怀孕期间的总体和长期/慢性药物使用情况。研究方法：这是跨国妊娠期药物使用研究的子研究，跨国妊娠期药物使用研究是一项2011年10月至2012年2月进行的横断面、基于网络的研究。我们纳入了来自欧洲的8097名孕妇或新妈妈。我们收集了关于总体和长期/慢性药物使用、因不孕症寻求医疗护理以及女性最终是否自发或在不孕症治疗的帮助下怀孕的数据。结果如下：与北方（15.2-17.5%）或东方（17.4-20.9%）相比，西欧不孕症的医疗保健接触率较低（患病率估计值：10.0-15.3%），但波兰的估计值最低（8.0%）。总体而言，660名（8.2%）妇女因不孕症寻求医疗保健，但自发受孕; 548名（6.8%）妇女在生育治疗的帮助下受孕，6889名（85.0%）妇女没有寻求帮助。任何药物的使用在三个组之间都是相当的（范围80.4-82.5%），但寻求不孕症帮助的妇女（21.8-24.6%）比没有长期/慢性药物的妇女（14.8%）更经常服用。结论：欧洲各国不孕症的医疗保健联系方式差异很大。由于不孕而有医疗接触的妇女在怀孕期间比没有医疗接触的妇女更经常使用慢性药物，这表明有更多的合并症和怀孕风险。
Aims: The aim of the study was two-fold: (i) to determine the prevalence of medical care contact for infertility in European countries; (ii) to map overall and long-term/chronic medication use during pregnancy in women who sought medical care due to infertility. Methods: This is a sub-study of the Multinational Medication Use in Pregnancy Study, a cross-sectional, web-based study conducted from October 2011 to February 2012. We included 8097 participants from Europe who were pregnant or new mothers. We collected data on overall and long-term/chronic medication use, medical care seeking due to infertility, and whether women eventually conceived spontaneously or with the aid of infertility treatment. Results: Medical care contact for infertility was lower in Western Europe (prevalence estimate: 10.0-15.3%), compared with Northern (15.2-17.5%) or Eastern (17.4-20.9%), but Poland had the lowest estimate (8.0%). Overall, 660 (8.2%) women sought medical care due to infertility but conceived spontaneously; 548 (6.8%) conceived aided by fertility treatment, and 6889 (85.0%) women did not seek help. Use of any medication was comparable across the three groups (range 80.4-82.5%), but women seeking help for infertility (21.8-24.6%) took more often long-term/chronic medications than women who did not (14.8%). Conclusion: Medical care contacts for infertility varies greatly across European countries. Women who had medical contact due to infertility used more often chronic medications in pregnancy than women who did not, pointing to more co-morbidities and risk pregnancies.