Gene and cell therapy in South Africa: Current status and future prospects

Gene and cell therapy in South Africa: Current status and future prospects
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DOI:
10.7196/samj.2019.v109i8b.13819
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发表时间:
2019-08-01
影响因子:
2.2
通讯作者:
Arbuthnot, P.
Arbuthnot, P.
中科院分区:
医学4区
文献类型:
--
作者:
Ely, A.;Bloom, K.;Arbuthnot, P.

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南非的传染性和非传染性疾病负担很重。目前的治疗措施很少能治愈疾病,相关的终身治疗给负担过重的卫生部门带来了相当大的压力。基因和细胞疗法为疾病管理提供了新的替代方案,提供了单一治疗和终身治愈的承诺。尽管挑战依然存在,但该领域的投资已经开始取得成果,在过去十年中,许多基因和细胞疗法已经进入市场。为了充分利用这些发展,重要的是在该国采取积极主动的办法,培养适当的人力和物质资源。
South Africa has a high disease burden resulting from communicable and non-communicable diseases. Current therapeutic interventions rarely result in a cure and the associated lifelong treatment places a considerable strain on an overburdened health sector. Gene and cell therapies present novel alternatives to disease management, offering the promise of a single treatment and a lifelong cure. Although challenges remain, investment in the field has started to bear fruit, with a number of gene and cell therapeutics reaching the market in the past decade. To take full advantage of these developments, it is important that a proactive approach to nurturing appropriate human and material resources is adopted in the country.