Sex chromatin and idiograms from rats exhibiting anomalies of the reproductive organs
Sex chromatin and idiograms from rats exhibiting anomalies of the reproductive organs
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表现出生殖器官异常的大鼠的性染色质和表意文字
DOI：
10.1002/ar.1091530110
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发表时间：
1965
期刊：
影响因子：
--
通讯作者：
L. G. Gumbreck
中科院分区：
文献类型：
--
作者：
J. E. Allison;A. J. Stanley;L. G. Gumbreck
在我们实验室饲养的一系列King‐Holtzmann杂交大鼠中出现了某些与生殖器官相关的异常情况。这些是不育的假两性男性，其中除睾丸外的整个生殖道都缺失;明显的男性表现出一侧或两侧的异位腹股沟环和睾丸;不育男性阴囊睾丸下降。将摩尔（'55）开发的染色性染色质的方法应用于大鼠肝脏、脊髓、睾丸和腮腺的细胞。然而，仅在肝细胞中清楚地显示出性别差异。福特和伍勒姆（'64）用于证明哺乳动物染色体的序列在骨髓细胞上呈现阳性结果。这种方法应用于肝脏和睾丸产生不满意的结果。
Certain anomalous conditions associated with the reproductive organs have arisen in a line of King‐Holtzmann hybrid rats maintained in our laboratory. These are sterile pseudohermaphroditic males in which the entire reproductive tract except the testes is missing; apparent males demonstrating an ectopic inguinal ring and testis on one or both sides; and sterile males with descended scrotal testes. The procedure developed by Moore ('55) for staining sex chromatin was applied to cells from liver, spinal cord, testis, and parotid gland of rats. A sex difference is clearly shown, however, only with the liver cells. Ford and Woollam's ('64) sequence for demonstrating mammalian chromosomes renders positive results on bone marrow cells. This method applied to liver and testis yields unsatisfactory results.