In vivo study of transverse carpal ligament stiffness using acoustic radiation force impulse (ARFI) imaging.
In vivo study of transverse carpal ligament stiffness using acoustic radiation force impulse (ARFI) imaging.
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DOI：
10.1371/journal.pone.0068569
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Li ZM
中科院分区：
文献类型：
--
作者：
Shen ZL;Vince DG;Li ZM
腕横韧带（TCL）形成腕管的掌侧边界，并可能对正中神经提供机械约束，导致腕管综合征。因此，TCL的机械性能是必不可少的，以更好地了解腕管综合征的病因。本研究的目的是利用声辐射力脉冲（ARFI）成像研究在体TCL刚度。使用Virtual Touch IQTM软件测量15名健康男性受试者的TCL剪切波速度（SWV）。还检查了皮肤和鱼际肌肉作为参考组织。此外，研究了测量位置和超声换能器压缩对SWV的影响。TCL的SWV取决于组织位置，肌肉附着区域内的SWV值大于肌肉附着区域外的SWV值。无压迫时TCL的SWV（5.21 ± 1.08 m/s）显著小于有压迫时（6.62 ± 1.18 m/s）。皮肤和鱼际肌肉的SWV测量也受到换能器压缩的影响，但与TCL的SWV相比程度不同。因此，为了标准化ARFI成像程序，建议保留一层超声凝胶，以最大限度地减少组织压缩的影响。本研究证明了ARFI成像用于评估TCL在体内的刚度特性的可行性，其具有识别组织的病理力学变化的潜力。
The transverse carpal ligament (TCL) forms the volar boundary of the carpal tunnel and may provide mechanical constraint to the median nerve, leading to carpal tunnel syndrome. Therefore, the mechanical properties of the TCL are essential to better understand the etiology of carpal tunnel syndrome. The purpose of this study was to investigate the in vivo TCL stiffness using acoustic radiation force impulse (ARFI) imaging. The shear wave velocity (SWV) of the TCL was measured using Virtual Touch IQTM software in 15 healthy, male subjects. The skin and the thenar muscles were also examined as reference tissues. In addition, the effects of measurement location and ultrasound transducer compression on the SWV were studied. The SWV of the TCL was dependent on the tissue location, with greater SWV values within the muscle-attached region than those outside of the muscle-attached region. The SWV of the TCL was significantly smaller without compression (5.21 ± 1.08 m/s) than with compression (6.62 ± 1.18 m/s). The SWV measurements of the skin and the thenar muscles were also affected by transducer compression, but to different extents than the SWV of the TCL. Therefore to standardize the ARFI imaging procedure, it is recommended that a layer of ultrasound gel be maintained to minimize the effects of tissue compression. This study demonstrated the feasibility of ARFI imaging for assessing the stiffness characteristics of the TCL in vivo, which has the potential to identify pathomechanical changes of the tissue.
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影响因子：
2.8
作者：
Holmes, Michael W. R.;Howarth, Samuel J.;Keir, Peter J.
通讯作者：
Keir, Peter J.
影响因子：
3.3
作者：
Shen, Zhilei Liu;Li, Zong-Ming
通讯作者：
Li, Zong-Ming
影响因子：
2.8
作者：
GARCIAELIAS, M;AN, KN;CHAO, EYS
通讯作者：
CHAO, EYS
DOI：
10.1016/j.jhsb.2005.04.019
发表时间：
2005-10-01
期刊：
JOURNAL OF HAND SURGERY-BRITISH AND EUROPEAN VOLUME
影响因子：
--
作者：
Kung, J;Budoff, JE;Luo, ZP
通讯作者：
Luo, ZP
影响因子：
2.9
作者：
Shen, Zhilei Liu;Li, Zong-Ming
通讯作者：
Li, Zong-Ming