QT interval prolongation during spontaneous episodes of hypoglycaemia in type 1 diabetes: the impact of heart rate correction
QT interval prolongation during spontaneous episodes of hypoglycaemia in type 1 diabetes: the impact of heart rate correction
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DOI：
10.1007/s00125-010-1802-0
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发表时间：
2010-09-01
期刊：
影响因子：
8.2
通讯作者：
Hejlesen, O. K.
中科院分区：
文献类型：
--
作者：
Christensen, T. F.;Tarnow, L.;Hejlesen, O. K.
目的/假设 1 型糖尿病低血糖发作期间观察到心率校正 QT 间期 (QTc) 延长。我们研究了自发性低血糖与 QT 间期之间的关系，并假设心率校正的选择会影响观察到的 QTc 变化。 方法 21 名 1 型糖尿病参与者（年龄 58 +/- 10 岁，糖尿病病程 34 +/- 12 年）进行了 72 小时的连续血糖和心电图监测。在低血糖期间测量 QT 和 RR 间期（血糖或连续血糖测量
Aims/hypothesis Prolongation of the heart rate corrected QT interval (QTc) is seen during episodes of hypoglycaemia in type 1 diabetes. We studied the relationship between spontaneous hypoglycaemia and the QT interval and hypothesised that the choice of heart rate correction affects the observed change in QTc.Methods Twenty-one participants with type 1 diabetes (aged 58 +/- 10 years with duration of diabetes 34 +/- 12 years) had continuous glucose and ECG monitoring for 72 h. QT and RR intervals were measured during hypoglycaemia (blood glucose or continuous glucose measurements