Subclass-restricted IgG polyclonal antibody production in mice injected with lipid A-rich lipopolysaccharides.
Subclass-restricted IgG polyclonal antibody production in mice injected with lipid A-rich lipopolysaccharides.
复制标题
注射富含脂质 A 的脂多糖的小鼠中产生亚类限制的 IgG 多克隆抗体。
DOI：
10.1084/jem.153.2.324
复制
发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Dixon,FJ
中科院分区：
文献类型：
--
作者：
Izui,S;Eisenberg,RA;Dixon,FJ
材料与方法小鼠。本研究所用小鼠均为6-10周龄。C57BL/6、C3H/ST和C3H/HeJ小鼠来自加利福尼亚州拉荷亚斯克里普斯诊所和研究基金会的小鼠繁育群体。C57BL/6纯合子裸鼠(nu/nu)和杂合子(nu/+)C57BL/6小鼠由斯克里普斯诊所和研究基金会的De Parks博士慷慨提供。用眼眶窦穿刺法采集血样，血清在-20℃保存直至使用。
Materials and Methods Mice. All mice used in this study were 6-10 wk old. C57BL/6, C3H/St, and C3H/HeJ mice were obtained from the mouse breeding colony of the Scripps Clinic and Research Foundation, La Jolla, Calif. Congenitally athymic nude (nu/nu) and heterozygous littermate (nu/+) C57BL/6 mice were kindly provided by Dr. DE Parks (Scripps Clinic and R~ earch Foundation). Blood samples were collected by orbital sinus puncture and sera were stored at-20 C until use.