A method for the fabrication of low-noise carbon fiber nanoelectrodes
A method for the fabrication of low-noise carbon fiber nanoelectrodes
复制标题
一种低噪声碳纤维纳米电极的制备方法
DOI：
10.1021/ac0008183
复制
发表时间：
2001-03-01
影响因子：
7.4
通讯作者：
Cheng, JK
中科院分区：
文献类型：
--
作者：
Huang, WH;Pang, DW;Cheng, JK
提出了一种制备低噪声碳纤维微电极（CFMEs）和碳纤维纳米电极（CFNEs）的简便方法。碳纤维被密封在玻璃毛细管的尖端。通过将凸出的碳纤维切割到所需的长度来制备cfme，并通过在火焰上蚀刻凸出的碳纤维形成纳米级尖端来实现cfne。cfne的尖端可以控制在100 ~ 300 nm的范围内。因此，CFMEs和CFNEs中没有环氧蜡的参与。通过扫描电镜检查CFMEs和CFNEs的实验结果表明，电极表面和玻璃/纤维界面非常光滑。因此，这些电极的玻璃/纤维产生的噪声比传统制造的电极低得多。电极使用CV、LSV、DPV和FSCV表征铁氰胺、儿茶酚胺（多巴胺，DA）、去甲肾上腺素（NE）和肾上腺素(E)和5-羟色胺（5-HT）神经递质。结果表明，CFMEs和CFNEs具有优异的电化学性能和较高的灵敏度，DA、NE和E的CV和DPV检出限分别为7.6 × 10（-8）、7.0 × 10（-8）和5.0 × 10(-8) mol/L， DA、NE和E的DPV检出限分别为4.0 × 10（-8）、1.0 × 10（-7）和2.2 × 10(-7) mol/L。本实验为制造高灵敏度、低噪声的cfme和cfne提供了一种新的简便方法。
A new and facile method has been developed for the fabrication of low-noise carbon fiber microelectrodes (CFMEs) and carbon fiber nanoelectrodes (CFNEs). The carbon fiber was name-fuse sealed in the tip of the glass capillary. The CFMEs were made by cutting the protruding carbon fiber to the desired length, and the CFNEs were achieved by etching the protruding carbon on the flame to form a nanometer-scale tip. The tip of CFNEs can be controlled within the range from 100 to 300 nm. Thus, no epoxy wax was involved in the CFMEs and CFNEs, The experimental results of inspecting CFMEs and CFNEs by scanning electron microscopy demonstrated that the surface of the electrodes and the glass/fiber interface are very smooth. Therefore, the noise caused by the glass/fiber of these electrodes is much lower than that of the electrodes fabricated conventionlly. The electrodes were characterized bq ferricyanide, catecholamine (dopamine, DA), norepinephrine (NE), and epinephrine (E)) and 5-hydroxytryptamine (5-HT) neurotransmitters using CV, LSV, DPV, and FSCV. The results showed that the CFMEs and CFNEs have very excellent electrochemical behavior and high sensitivity, The CV and DPV detection limits of DA, NE, and E are 7.6 x 10(-8), 7.0 x 10(-8), and 5.0 x 10(-8) mol/L, and the DPV detection limits of DA, NE, and E are 4.0 x 10(-8), 1.0 x 10(-7), and 2.2 x 10(-7) mol/L, respectively. This experiment offers a new and facile method for the fabrication of CFMEs and CFNEs of very high sensitivity and low noise.