Intracardiac MR imaging (ICMRI) guiding-sheath with amplified expandable-tip imaging and MR-tracking for navigation and arrythmia ablation monitoring: Swine testing at 1.5 and 3T.
Intracardiac MR imaging (ICMRI) guiding-sheath with amplified expandable-tip imaging and MR-tracking for navigation and arrythmia ablation monitoring: Swine testing at 1.5 and 3T.
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心内 MR 成像 (ICMRI) 引导鞘，具有放大的可扩展尖端成像和 MR 跟踪，用于导航和心律失常消融监测：1.5 和 3T 的猪测试。
DOI：
10.1002/mrm.29168
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发表时间：
2022-06
影响因子：
3.3
通讯作者：
Halperin HR
中科院分区：
文献类型：
--
作者：
Schmidt EJ;Olson G;Tokuda J;Alipour A;Watkins RD;Meyer EM;Elahi H;Stevenson WG;Schweitzer J;Dumoulin CL;Johnson T;Kolandaivelu A;Loew W;Halperin HR
开发一种可偏转的心内磁共振成像(ICMRI)引导鞘，用于在MR引导的电生理(EP)介入射频(500 KHz)消融(RFA)期间加速成像。要求包括在心腔内以三到五倍的表面线圈信噪比进行成像、血管插入、可操纵的主动导航进入心腔、使用消融导管进行手术以及安全水平的MR诱导加热。ICMRI的6 mm外径(OD)金属编织轴的内腔外径为2.6 mm，用于消融导管的插入。ICMRI 1米轴上的微型巴伦(MBaluns)减少了身体线圈感应的加热。远端是一个折叠的星形成像线圈，安装在一个可扩展的框架上，集成了一个克服电缆损耗的微型低噪声放大器。手柄激活的可动轴扩展成像线圈，外径35 mm，用于心腔内成像。四个磁流变跟踪微线圈实现了导航和运动补偿，当展开时呈四面体形状。第二个手柄杠杆使末端远端偏转。使用带有突出的可偏转EP导管的ICMRI进行MR跟踪导航，并使用专用3D切片器用户界面进行RFA。在猪身上进行3T和1.5T的ICMRI测试，以评估(A)加热，(B)心腔通路，(C)成像视野和SNR，以及(D)术中RFA病变监测。相对于身体和脊柱阵列，3T和1.5T成像SNR显示心脏在4×4×4 cm~3视野下的SNR提高了400%。使用MBaluns的ICMRI在航行期间符合ASTM/IEC加热限制。顶端偏转可使ICMRI和EP导管进入心房和脑室。使用ICMRI进行急性病变长反转时间-T1加权三维成像(TWILITE)消融监测需要5：30分钟，是仅使用表面阵列所需时间的一半。ICMRI辅助EP导管导航至困难靶点，加速RFA监测。
Develop a deflectable intracardiac MR imaging (ICMRI) guiding‐sheath to accelerate imaging during MR‐guided electrophysiological (EP) interventions for radiofrequency (500 kHz) ablation (RFA) of arrythmia. Requirements include imaging at three to five times surface‐coil SNR in cardiac chambers, vascular insertion, steerable‐active‐navigation into cardiac chambers, operation with ablation catheters, and safe levels of MR‐induced heating. ICMRI’s 6 mm outer‐diameter (OD) metallic‐braided shaft had a 2.6 mm OD internal lumen for ablation‐catheter insertion. Miniature‐Baluns (MBaluns) on ICMRI’s 1 m shaft reduced body‐coil‐induced heating. Distal section was a folded “star”‐shaped imaging‐coil mounted on an expandable frame, with an integrated miniature low‐noise‐amplifier overcoming cable losses. A handle‐activated movable‐shaft expanded imaging‐coil to 35 mm OD for imaging within cardiac‐chambers. Four MR‐tracking micro‐coils enabled navigation and motion‐compensation, assuming a tetrahedron‐shape when expanded. A second handle‐lever enabled distal‐tip deflection. ICMRI with a protruding deflectable EP catheter were used for MR‐tracked navigation and RFA using a dedicated 3D‐slicer user‐interface. ICMRI was tested at 3T and 1.5T in swine to evaluate (a) heating, (b) cardiac‐chamber access, (c) imaging field‐of‐view and SNR, and (d) intraprocedural RFA lesion monitoring. The 3T and 1.5T imaging SNR demonstrated >400% SNR boost over a 4 × 4 × 4 cm3 FOV in the heart, relative to body and spine arrays. ICMRI with MBaluns met ASTM/IEC heating limits during navigation. Tip‐deflection allowed navigating ICMRI and EP catheter into atria and ventricles. Acute‐lesion long‐inversion‐time‐T1‐weighted 3D‐imaging (TWILITE) ablation‐monitoring using ICMRI required 5:30 min, half the time needed with surface arrays alone. ICMRI assisted EP‐catheter navigation to difficult targets and accelerated RFA monitoring.
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DOI：
10.1002/jmri.1880080138
发表时间：
1998-01-01
期刊：
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING
影响因子：
--
作者：
Martin, AJ;McLoughlin, RF;Rutt, BK
通讯作者：
Rutt, BK
DOI：
10.1111/j.1540-8167.2006.00491.x
发表时间：
2006-07-01
影响因子：
2.7
作者：
Mansour, M;Refaat, M;Ruskin, JN
通讯作者：
Ruskin, JN
影响因子：
4.6
作者：
Alipour, Akbar;Meyer, Eric S.;Schmidt, Ehud J.
通讯作者：
Schmidt, Ehud J.
影响因子：
3
作者：
Galand, Vincent;Pavin, Dominique;Martins, Raphael P.
通讯作者：
Martins, Raphael P.
影响因子：
2.5
作者：
Fedorov, Andriy;Beichel, Reinhard;Kalpathy-Cramer, Jayashree;Finet, Julien;Fillion-Robin, Jean-Christophe;Pujol, Sonia;Bauer, Christian;Jennings, Dominique;Fennessy, Fiona;Sonka, Milan;Buatti, John;Aylward, Stephen;Miller, James V.;Pieper, Steve;Kikinis, Ron
通讯作者：
Kikinis, Ron