What can be learned about motoneurone properties from studying firing patterns?
What can be learned about motoneurone properties from studying firing patterns?
复制标题
通过研究放电模式可以了解运动神经元的哪些特性？
DOI：
10.1007/978-1-4615-0713-0_24
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发表时间：
2002
影响因子：
--
通讯作者：
Binder,MarcD
中科院分区：
文献类型：
--
作者：
Powers,RandallK;Türker,KemalS;Binder,MarcD
紧张性放电神经元的放电模式受其突触前输入的特征和其内在属性的影响。运动神经元放电的规律性被认为反映了其显著的锋电位后超极化（AHP）。当运动神经元以稳定的平均速率发射时，尖峰间期的分布由突触噪声的幅度和频率内容以及由于AHP引起的尖峰之后的兴奋性降低来确定。本文考虑如何运动神经元放电统计可以用来估计AHP轨迹以及运动神经元的兴奋性输入的敏感性。
The discharge patterns of tonically-firing neurones are influenced by both the characteristics of their presynaptic input and their intrinsic properties. The regularity of the discharge of motoneurones is thought to reflect their prominent post-spike afterhyperpolarization (AHP). When a motoneurone fires at steady mean rate, the distribution of interspike intervals is determined by the amplitude and frequency content of the synaptic noise together with the decrease in excitability following a spike due to AHP. This paper considers how motoneurone discharge statistics can be used to estimate AHP trajectories as well as a motoneurone’s sensitivity to excitatory input.