Risk factors associated with the development of aspiration pneumonia in patients receiving radiotherapy for head and neck cancer: retrospective study
Risk factors associated with the development of aspiration pneumonia in patients receiving radiotherapy for head and neck cancer: retrospective study
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DOI：
10.1002/hed.26314
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发表时间：
2020-06-01
影响因子：
2.9
通讯作者：
Umeda, Masahiro
中科院分区：
文献类型：
--
作者：
Kawashita, Yumiko;Morimoto, Shimpei;Umeda, Masahiro
背景头颈部癌症患者接受放射治疗时可发生吸入性肺炎。吸入性肺炎的发病率和相关的危险因素的测定，可以方便地识别高风险patients.Methods在这项回顾性研究中，我们确定了吸入性肺炎的发病率在357例接受放疗沿着口腔护理头颈部癌症。结果吸入性肺炎的发生率为17.6%。下咽癌、3级口腔粘膜炎和鼻饲管喂养是独立的危险因素。此外，吸入性肺炎的发展是一个主要的影响，停止radiation.Conclusion，约六分之一的患者发展吸入性肺炎，尽管适当的口腔护理在放疗头颈部癌症。放疗期间吸入性肺炎可能会对头颈部癌症的治疗产生不利影响。
Background Patients with head and neck cancer who are receiving radiotherapy can develop aspiration pneumonia. Determination of the incidence of aspiration pneumonia and the associated risk factors could facilitate the identification of high-risk patients.Methods In this retrospective study, we determined the incidence of aspiration pneumonia in 357 patients receiving radiotherapy along with oral care for head and neck cancer. We also performed univariate and multivariable logistic regression analyses to investigate the risk factors for this complication.Results The incidence of aspiration pneumonia was 17.6%. Hypopharyngeal cancer, grade 3 oral mucositis, and nasogastric tube feeding were independent risk factors. Moreover, the development of aspiration pneumonia was one of the major effects on the discontinuation of radiotherapy.Conclusion Approximately, one-sixth of the patients developed aspiration pneumonia despite appropriate oral care during radiotherapy for head and neck cancer. Aspiration pneumonia during radiotherapy could adversely affect head and neck cancer management.