Cross-coupling Reaction between Enol Phosphates and Organoaluminium Compounds in the Presence of Palladium(0) Catalyst
Cross-coupling Reaction between Enol Phosphates and Organoaluminium Compounds in the Presence of Palladium(0) Catalyst
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钯(0)催化剂存在下烯醇磷酸酯与有机铝化合物的交叉偶联反应
DOI：
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发表时间：
1984
期刊：
影响因子：
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通讯作者：
H. Nozaki
中科院分区：
文献类型：
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作者：
K. Takai;M. Sato;K. Oshima;H. Nozaki
标题反应在催化量的四(三苯基膦)钯(0)的存在下，在室温下在1，2-二氯乙烷中以良好到极好的产率提供了烷基化偶联产物。C(Sp2)-O裂解下的偶联反应以立体专一性进行。该反应不影响共存的硫化乙烯基团。这一特征使1，2-和1，3-羰基转位可以通过苯硫基取代的烯醇磷酸盐进行烷基化或不通过烷基化进行。
The title reaction in the presence of a catalytic amount of tetrakis(triphenylphosphine)palladium(0) affords alkylative coupling products in good to excellent yields in 1,2-dichloroethane at room temperature. This coupling reaction under C(sp2)–O cleavage proceeds stereospecifically. The reaction does not affect a coexisting vinyl sulfide group. This feature enables 1,2- and 1,3-carbonyl transposition with or without alkylation via phenylthio-substituted enol phosphates.