The Neural Dynamics of Fronto-Parietal Networks in Childhood Revealed using Magnetoencephalography.
The Neural Dynamics of Fronto-Parietal Networks in Childhood Revealed using Magnetoencephalography.
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DOI：
10.1093/cercor/bhu271
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发表时间：
2015-10
期刊：
影响因子：
--
通讯作者：
Scerif G
中科院分区：
文献类型：
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作者：
Astle DE;Luckhoo H;Woolrich M;Kuo BC;Nobre AC;Scerif G
我们在头脑中记住信息的能力是有限的，需要高度的认知控制，并且是许多后续认知过程所必需的。特别是儿童，在一次又一次的试验中，他们如何设法招募认知控制来为记忆服务，这一点是高度可变的。额顶叶网络通常在需要这种认知控制的条件下被招募，经历长期的发展。我们首次探讨了额顶叶活动的动态变化是否可以解释儿童视觉短期记忆（VSTM）测试的变异性。我们使用脑磁图（MEG）记录了9至12岁儿童和成人执行VSTM任务的振荡脑活动。我们结合时间独立成分分析（伊卡）与一般的线性建模，以测试是否与VSTM的性能在一个试验的基础上，额顶叶活动的强度。在儿童中，右侧额顶叶网络中的慢频率（4-7 Hz）活动预测了这些记忆项目随后被检索的准确性，但成年人则不然。这些研究结果表明，不一致的使用预期控制机制有助于显着的审判，以审判的VSTM维护性能的变化。
Our ability to hold information in mind is limited, requires a high degree of cognitive control, and is necessary for many subsequent cognitive processes. Children, in particular, are highly variable in how, trial-by-trial, they manage to recruit cognitive control in service of memory. Fronto-parietal networks, typically recruited under conditions where this cognitive control is needed, undergo protracted development. We explored, for the first time, whether dynamic changes in fronto-parietal activity could account for children's variability in tests of visual short-term memory (VSTM). We recorded oscillatory brain activity using magnetoencephalography (MEG) as 9- to 12-year-old children and adults performed a VSTM task. We combined temporal independent component analysis (ICA) with general linear modeling to test whether the strength of fronto-parietal activity correlated with VSTM performance on a trial-by-trial basis. In children, but not adults, slow frequency theta (4–7 Hz) activity within a right lateralized fronto-parietal network in anticipation of the memoranda predicted the accuracy with which those memory items were subsequently retrieved. These findings suggest that inconsistent use of anticipatory control mechanism contributes significantly to trial-to-trial variability in VSTM maintenance performance.