Characteristics and variations of in vivo Schlemm's canal and collector channel microstructures in enhanced-depth imaging optical coherence tomography
Characteristics and variations of in vivo Schlemm's canal and collector channel microstructures in enhanced-depth imaging optical coherence tomography
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DOI：
10.1136/bjophthalmol-2016-309295
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发表时间：
2017-06-01
影响因子：
4.1
通讯作者：
Park, Sung Chul
中科院分区：
文献类型：
--
作者：
Li, Pengcheng;Butt, Anum;Park, Sung Chul
背景/目的利用增强深度成像（EDI）光学相干断层扫描（OCT）技术对活体Schlemm管（SC）和收集通道（CC）的微观结构进行研究。方法在鼻和颞部利姆布斯前瞻性地获得连续水平EDI OCT B扫描（81次扫描，15 × 5度矩形）。通过在每次B超中描绘其管腔来测量SC横截面积（CSA）。对连接至SC的CC进行计数。SC CSA和CC的数量之间进行了比较鼻和temporalareas.Results 11眼（11名正常人），平均年龄28 ± 5岁。在EDI OCT B扫描中，SC和CC的界限清楚，具有良好的重复性和再现性（组内相关系数分别为0.830-0.886和0.793;所有p
Background/aims To characterise in vivo Schlemm's canal (SC) and collector channels (CC) microstructures using enhanced-depth imaging (EDI) optical coherence tomography (OCT).Methods Serial horizontal EDI OCT B-scans (81 scans, 15x5 degrees rectangle) were prospectively obtained in the nasal and temporal limbus. SC cross-sectional area (CSA) was measured by delineating its lumen in each B-scan. CCs connected to SC were counted. SC CSA and the number of CCs were compared between the nasal and temporal areas.Results Eleven eyes (11 normal subjects) were included (mean age, 28 +/- 5 years). SC and CCs were clearly demarcated in EDI OCT B-scans with excellent repeatability and reproducibility (intraclass correlation coefficients, 0.830-0.886 and 0.793, respectively; all p