Diagnosis and Management of Acquired Pure Red Cell Aplasia

Diagnosis and Management of Acquired Pure Red Cell Aplasia
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DOI:
10.1016/j.hoc.2009.01.009
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发表时间:
2009-04-01
影响因子:
2.4
通讯作者:
Fujishima, Naohito
Fujishima, Naohito
中科院分区:
医学4区
文献类型:
--
作者:
Sawada, Kenichi;Hirokawa, Makoto;Fujishima, Naohito

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Pure red cell aplasia is a syndrome characterized by a severe normocytic anemia, reticulocytopenia, and absence of erythroblasts from an otherwise normal bone marrow. Although the causes and natural course of this syndrome are variable,and although the anemia in some patients can be managed by treatment of an underlying inflammatory or neoplastic disease, the pathogenesis of a large number of cases is autoimmune, including those associated with thymoma, and are best managed with immunosuppressive therapy.