Offering to share: How to put heads together in autism neuroimaging
Offering to share: How to put heads together in autism neuroimaging
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DOI：
10.1007/s10803-006-0352-2
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发表时间：
2008-01-01
影响因子：
3.9
通讯作者：
Colamarino, Sophia A.
中科院分区：
文献类型：
--
作者：
Belmonte, Matthew K.;Mazziotta, John C.;Colamarino, Sophia A.
自闭症神经成像的数据共享存在科学，技术和社会障碍。我们概述了数据共享方案的必要性，该方案将成像与其他表型指标和遗传学指标相结合，定义了衍生数据可比性的要求和原始数据的建议，概述了包括多光谱结构和弥散张量成像和可选扩展的核心协议，提供了前瞻性、无混淆的规范性数据的收集，并将共享和协作开发不仅扩展到数据，还扩展到应用于这些数据的分析工具和方法。这些要求中的一个主题是，在为实验室提供共同标准的同时，需要在各个实验室中保留创造性方法和冒险精神。
Data sharing in autism neuroimaging presents scientific, technical, and social obstacles. We outline the desiderata for a data-sharing scheme that combines imaging with other measures of phenotype and with genetics, defines requirements for comparability of derived data and recommendations for raw data, outlines a core protocol including multispectral structural and diffusion-tensor imaging and optional extensions, provides for the collection of prospective, confound-free normative data, and extends sharing and collaborative development not only to data but to the analytical tools and methods applied to these data. A theme in these requirements is the need to preserve creative approaches and risk-taking within individual laboratories at the same time as common standards are provided for these laboratories to build on.