RECOVERY FROM END-STAGE RENAL-DISEASE
RECOVERY FROM END-STAGE RENAL-DISEASE
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DOI：
10.1016/s0272-6386(12)80593-2
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发表时间：
1990-01-01
影响因子：
13.2
通讯作者：
FERGUSON, CW
中科院分区：
文献类型：
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作者：
SEKKARIE, MA;PORT, FK;FERGUSON, CW
为了评价肾病学家标记为终末期肾病（ESRD）患者的肾功能恢复率和相关因素，使用了密歇根州肾脏登记处的数据库。对1976年至1985年期间报告开始接受ESRD治疗的所有患者（N = 7，404）进行了评价，不包括急性肾小管坏死（ATN）患者或移植病例。虽然糖尿病和囊性疾病导致的ESRD患者的恢复率低于平均水平，但与全身性疾病、血管病变和新月体相关的肾小球肾炎患者的恢复率高出三倍至四倍。白色人种、年龄较大和ESRD较晚的年份与显著较高的恢复率相关。接受腹膜透析或血液透析的患者的恢复率没有显著差异。约48%的恢复者在ESRD后6个月内恢复，74%在1年内恢复，75%的病例持续至少1年。作者得出结论，在诊断终末期肾病时应谨慎;应寻求和评估恢复的可能性，特别是考虑早期肾移植时。
To evaluate the rate and associated factors for recovery of renal function in patients labeled by their nephrologists as having end-stage renal disease (ESRD), the data base of the Michigan Kidney Registry was used. All patients reported as starting treatment for ESRD between 1976 and 1985 (N = 7,404) were evaluated, excluding patients with acute tubular necrosis (ATN) or transplantation cases. While patients with ESRD due to diabetes and cystic diseases had lower recovery rates than average, patients with glomerulonephritis associated with a systemic illness, vasculopathies, and crescents had threefold to fourfold higher recovery rates. White race, older age, and later year of ESRD were associated with significantly higher recovery rates. Recovery rates did not differ substantially for patients receiving peritoneal dialysis or hemodialysis. Recovery occurred within 6 months of ESRD in approximately 48% of those recovering, 74% within 1 year, and lasted at least 1 year in 75% of the cases. The authors conclude that caution should be applied when the diagnosis of ESRD is made; the possibility of recovery should be sought and assessed, especially when early renal transplantation is considered.