Mycetoma: The Spectrum of Clinical Presentation.
Mycetoma: The Spectrum of Clinical Presentation.
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DOI：
10.3390/tropicalmed3030097
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发表时间：
2018-09-04
影响因子：
2.9
通讯作者：
Hay R
中科院分区：
文献类型：
--
作者：
Fahal AH;Suliman SH;Hay R
足菌肿是一种慢性传染病，最近被世界卫生组织（WHO）指定为一种被忽视的热带病，在热带和亚热带地区流行。它是指感染性有机体，真菌（真菌瘤）或丝状细菌（放线菌瘤）植入皮下组织，从感染扩散到皮肤、骨骼和皮下部位，导致健康相关和社会经济问题。与其他被忽视热带病一样，足菌肿最常见于农村地区最贫困的人群，他们获得卫生保健的机会较少。这些微生物形成小的微菌落，通过窦道排出到皮肤表面，或者钻入其他邻近组织，包括骨骼。本文介绍足菌肿的临床特征，因为早期识别是早期诊断和适当治疗的关键，包括手术。由于这些病变大多是无痛的，而且大多数感染者出现较晚且病情进展，因此简化早期识别是一项重要的公共卫生目标。
Mycetoma is a chronic infection, newly designated by the World Health Organization (WHO) as a neglected tropical disease, which is endemic in tropical and subtropical regions. It follows implantation of infectious organisms, either fungi (eumycetomas) or filamentous bacteria (actinomycetomas) into subcutaneous tissue, from where infection spreads to involve skin, bone and subcutaneous sites, leading to both health related and socioeconomic problems. In common with other NTDs, mycetoma is most often seen in rural areas amongst the poorest of people who have less access to health care. The organisms form small microcolonies that are discharged onto the skin surface via sinus tracts, or that can burrow into other adjacent tissues including bone. This paper describes the clinical features of mycetoma, as early recognition is a key to early diagnosis and the institution of appropriate treatment including surgery. Because these lesions are mostly painless and the majority of infected individuals present late and with advanced disease, simplifying early recognition is an important public health goal.