The war on cryptococcosis: A Review of the antifungal arsenal.
The war on cryptococcosis: A Review of the antifungal arsenal.
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DOI:
10.1590/0074-02760170391
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发表时间:
2018
影响因子:
2.8
通讯作者:
Perfect JR
中科院分区:
文献类型:
--
作者:
Mourad A;Perfect JR
Cryptococcal meningitis is the most common central nervous system infection in the world today. It occurs primarily, but not exclusively, in immunocompromised individuals and despite substantial improvement in management of clinical events like AIDS, the numbers of cases of cryptococcosis remain very high. Unfortunately, despite several antifungal agents available for treatment, morbidity and mortality rates remain high with this fungal infection. In this Review, we will describe the treatments and strategies for success, identify the failures, and provide insights into the future developments / improvements for management. This sugar-coated yeast can play havoc within the human brain. Our goals must be to either prevent or diagnose disease early and treat aggressively with all our clinical tools when disease is detected.
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影响因子:
3.7
作者:
Dromer F;Bernede-Bauduin C;Guillemot D;Lortholary O;French Cryptococcosis Study Group
通讯作者:
French Cryptococcosis Study Group
影响因子:
168.9
作者:
Brouwer, AE;Rajanuwong, A;Harrison, TS
通讯作者:
Harrison, TS
DOI:
10.1097/qai.0000000000000484
发表时间:
2015-04-15
影响因子:
3.6
作者:
Kaplan, Jonathan E.;Vallabhaneni, Snigdha;Park, Benjamin
通讯作者:
Park, Benjamin
影响因子:
3.8
作者:
DEGANS, J;PORTEGIES, P;STAM, J
通讯作者:
STAM, J
影响因子:
11.8
作者:
Graybill, JR;Sobel, J;Dismukes, W
通讯作者:
Dismukes, W