Rapid adrenocortical recovery after short-term glucocorticoid therapy.
Rapid adrenocortical recovery after short-term glucocorticoid therapy.
复制标题
短期糖皮质激素治疗后肾上腺皮质快速恢复。
DOI：
10.1001/archpedi.1981.02130330002002
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发表时间：
1981
影响因子：
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通讯作者：
J. Corrigan
中科院分区：
文献类型：
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作者：
E. Lightner;H. Johnson;J. Corrigan
对13例急性白血病患儿进行了大剂量糖皮质激素（强的松，2 mg/kg/d）间歇治疗，每4个月治疗1个月，观察肾上腺皮质功能恢复时间。数据表明，肾上腺对压力的反应能力从这种治疗中迅速恢复。我们的研究结果清楚地表明，常规补充糖皮质激素治疗这些患者在临床应激期发生后超过9天的糖皮质激素治疗是不必要的。
The recovery time of adrenocortical function was studied in 13 children receiving intermittent high-dosage glucocorticoid therapy (prednisone, 2 mg/kg/day) for one month out of every four months as treatment for acute leukemia. The data indicate that the adrenal gland's ability to respond to stress recovers rapidly from such treatment. The results of our study clearly show that routine supplementation with glucocorticoid therapy in these patients during periods of clinical stress occurring later than nine days after glucocorticoid therapy is not warranted.