Factor analysis of the metabolic syndrome among elderly Koreans - the South-west Seoul Study
Factor analysis of the metabolic syndrome among elderly Koreans - the South-west Seoul Study
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DOI：
10.1046/j.1464-5491.2003.00890.x
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发表时间：
2003-02-01
影响因子：
3.5
通讯作者：
Baik, SH
中科院分区：
文献类型：
--
作者：
Choi, KM;Lee, J;Baik, SH
目的探讨代谢综合征的组成部分之间的关系，并探讨是否胰岛素抵抗统一的聚类的组成部分，在城市老年韩国人使用探索性因素analysis.Methods我们包括1314名非糖尿病受试者年龄在60岁以上，从一个横断面研究，这是在1999年进行的首尔，韩国。采用方差最大正交旋转主成分分析法对代谢综合征各成分进行因子分析。葡萄糖耐量受损、血脂异常、高血压和肥胖是主要的疾病。肥胖和血脂异常变量密切相关，并加载在相同的因素。结论胰岛素抵抗不是韩国城市老年人代谢综合征的唯一致病因素。虽然代谢综合征的组成部分密切相关，发现一个以上的因素表明，一个以上的病理生理机制的基础上充分表达的代谢综合征老年韩国人。
Aims To examine the relationship between the components of the metabolic syndrome and to explore whether insulin resistance unifies the clustering of components of the metabolic syndrome among urban elderly Koreans using exploratory factor analysis.Methods We included 1314 non-diabetic subjects over the age of 60 years, selected from a cross-sectional study, which was conducted in 1999 in Seoul, Korea. Factor analysis was carried out using the principle components analysis with Varimax orthogonal rotation of the components of the metabolic syndrome.Results We found four major factors of cardiovascular disease risk variables in our study subjects. Impaired glucose tolerance, dyslipidaemia, hypertension and obesity aggregated as the major domain. Obesity and dyslipidaemia variables were closely related and loaded on the same factor. However, hypertension was not linked closely with other factors of the metabolic syndrome.Conclusions Insulin resistance is not the only contributor to the metabolic syndrome among urban elderly Koreans. Although the components of the metabolic syndrome were closely related, the finding of more than one factor suggests that more than one pathophysiological mechanism underlies full expression of the metabolic syndrome among elderly Koreans.