Pleural liquid pressure in dogs measured using a rib capsule.
Pleural liquid pressure in dogs measured using a rib capsule.
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使用肋骨囊测量狗的胸膜液压力。
DOI：
10.1152/jappl.1985.59.2.597
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Lai-Fook,SJ
中科院分区：
文献类型：
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作者：
Wiener-Kronish,JP;Gropper,MA;Lai-Fook,SJ
我们已经开发了一种微创方法来测量胸膜空间液体的静水压力。将充满液体的胶囊粘接在肋骨上，并在胸膜壁层上开一个小孔，使胶囊中的液体与胸膜空间直接交流。压力可以通过连接在胶囊上的应变计传感器连续测量。肋骨囊不会扭曲胸膜间隙，也不需要切除肋间肌。气胸在穿刺胸膜壁层时很容易被发现。我们研究了身高对15只麻醉自主呼吸犬胸膜压力的影响。平头、平头、仰卧和俯卧体位胸膜压垂直梯度分别为0.53、0.42、0.46和0.23 cmH2O/cm高度。这些垂直梯度远小于流体静力值（1 cmH2O/cm），表明胸膜液不处于流体静力平衡状态。在大多数体位中，胸膜液体压力的大小内插到胸部中部水平与死后确定的平均肺（表面）压力相似。提示胸膜液压力与肺静后坐力密切相关。
We have developed a minimally invasive method for measuring the hydrostatic pressure in the pleural space liquid. A liquid-filled capsule is bonded into a rib and a small hole is cut in the parietal pleura to allow direct communication between the liquid in the capsule and the pleural space. The pressure can be measured continuously by a strain gauge transducer connected to the capsule. The rib capsule does not distort the pleural space or require removal of intercostal muscle. Pneumothoraces are easily detected when they occur inadvertently on puncturing the parietal pleura. We examined the effect of height on pleural pressure in 15 anesthetized spontaneously breathing dogs. The vertical gradients in pleural pressure were 0.53, 0.42, 0.46, and 0.23 cmH2O/cm height for the head-up, head-down, supine, and prone body positions, respectively. These vertical gradients were much less than the hydrostatic value (1 cmH2O/cm), indicating that the pleural liquid is not in hydrostatic equilibrium. In most body positions the magnitudes of pleural liquid pressure interpolated to midchest level were similar to the mean transpulmonary (surface) pressure determined postmortem. This suggests that pleural liquid pressure is closely related to the lung static recoil.