Toxic effects of irradiation or doxorubicin in combination with moderate whole-body hyperthermia on bone marrow in rats.
Toxic effects of irradiation or doxorubicin in combination with moderate whole-body hyperthermia on bone marrow in rats.
复制标题
辐射或多柔比星联合中度全身热疗对大鼠骨髓的毒性作用。
DOI：
10.1007/978-3-642-83263-5_10
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
R. Engelhardt
中科院分区：
文献类型：
--
作者：
W. Hinkelbein;M. Birmelin;D. Menger;R. Engelhardt
The therapeutic benefit that accrues from combining hyperthermia with other cancer treatment modalities implies enhancement of tumor control but not of normal tissue damage. In experimental tumor models the interactions between heat and cytostatic drugs (Bertino et al. 1984) or irradiation (Mooibroek et al. 1984; Dewhirst et al. 1985) are well known. However, only a few studies have been performed in normal tissues (Hume et al. 1983; Law et al. 1985), especially in critical organs for defined treatment regimes.
