Ankle-brachial index and cardiovascular outcomes in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial.
Ankle-brachial index and cardiovascular outcomes in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial.
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旁路血管成形术血运重组研究中的脚踝 - 桥梁指数和心血管结局2糖尿病试验。
DOI：
10.1016/j.ahj.2012.06.017
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发表时间：
2012-10
影响因子：
4.8
通讯作者：
Kelsey, Sheryl F.
中科院分区：
文献类型：
--
作者：
Abbott, J. Dawn;Lombardero, Manuel S.;Barsness, Gregory W.;Pena-Sing, Ivan;Buitron, L. Virginia;Singh, Premranjan;Woodhead, Gail;Tardif, Jean-Claude;Kelsey, Sheryl F.
Peripheral arterial disease (PAD) increases cardiovascular risk in many patient populations. The risks associated with an abnormal ankle-brachial index (ABI) in patients with type 2 diabetes (T2D) and stable coronary artery disease (CAD) have not been well described with respect to thresholds and types of cardiovascular events. We examined 2368 patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial that underwent ABIassessment at baseline. Death and major cardiovascular events (death, myocardial infarction (MI) and stroke) during follow-up (average 4.3 years) were assessed across the ABI spectrum and by categorizedABI: low (≤0.90), normal (0.91–1.3), high (>1.3), or non-compressible. A total of 12,568 person-years were available for mortality analysis. During follow-up, 316 patients died and 549 suffered major cardiovascular events. After adjustment for potential confounders, with normal ABI as the referent group, a low ABI conferred an increased risk of death (relative risk (RR) 1.6; C.I. 1.2, 2.2; p=.0005) and major cardiovascular events (RR 1.4; C.I. 1.1, 1.7; p=.004). Patients with a high ABI had similar outcomes as patients with a normal ABI, but risk again increased in patients with a non-compressible ABI with a risk of death (RR1.9; C.I. 1.3, 2.8; p=.001) and major cardiovascular event (RR 1.5, C.I. 1.1, 2.1; p=.01). In patients with CAD and T2D ABI screening and identification of ABI abnormalities including a low ABI (<1.0) or non-compressible artery provide incremental prognostic information.
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影响因子：
24
作者：
Rooke TW;Hirsch AT;Misra S;Sidawy AN;Beckman JA;Findeiss LK;Golzarian J;Gornik HL;Halperin JL;Jaff MR;Moneta GL;Olin JW;Stanley JC;White CJ;White JV;Zierler RE;Society for Cardiovascular Angiography and Interventions;Society of Interventional Radiology;Society for Vascular Medicine;Society for Vascular Surgery
通讯作者：
Society for Vascular Surgery
影响因子：
120.7
作者：
Fowkes, F. G. R.;Murray, G. D.;Butcher, I.;Heald, C. L.;Lee, R. J.;Chambless, L. E.;Folsom, A. R.;Hirsch, A. T.;Dramaix, M.;deBacker, G.;Wautrecht, J-C.;Kornitzer, M.;Newman, A. B.;Cushman, M.;Sutton-Tyrrell, K.;Lee, A. J.;Price, J. F.;d'Agostino, R. B.;Murabito, J. M.;Norman, P. E.;Jamrozik, K.;Curb, J. D.;Masaki, K. H.;Rodriquez, B. L.;Dekker, J. M.;Bouter, L. M.;Heine, R. J.;Nijpels, G.;Stehouwer, C. D. A.;Ferrucci, L.;McDermott, M. M.;Stoffers, H. E.;Hooi, J. D.;Knottnerus, J. A.;Ogren, M.;Hedblad, B.;Witteman, J. C.;Breteler, M. M. B.;Hunink, M. G. M.;Hofman, A.;Criqui, M. H.;Langer, R. D.;Fronek, A.;Hiatt, W. R.;Hamman, R.;Resnick, H. E.;Guralnik, J.;McDermott, M. M.
通讯作者：
McDermott, M. M.
影响因子：
4.8
作者：
Brooks, Maria Mori;Barsness, Gregory;Tardif, Jean-Claude
通讯作者：
Tardif, Jean-Claude
影响因子：
3.5
作者：
Quiles, Juan;Morillas, Pedro;Gonzalez-Juanatey, Jose Ramon
通讯作者：
Gonzalez-Juanatey, Jose Ramon
影响因子：
2.8
作者：
Brooks, Maria Mori;Frye, Robert L.;Orchard, Trevor J.
通讯作者：
Orchard, Trevor J.