Role of the nonhuman primate for research related to women's health
Role of the nonhuman primate for research related to women's health
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DOI：
10.1093/ilar.45.2.212
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发表时间：
2004-01-01
期刊：
影响因子：
2.5
通讯作者：
Archer, DF
中科院分区：
文献类型：
--
作者：
Archer, DF
这一概述的医疗问题，影响妇女的现状是有关目前的研究病理生理学和治疗干预使用非人灵长类动物，以证明在妇女的疾病过程的研究的灵长类动物模型的效用。目前的医学文献对妇女的健康进行了比较，非人类灵长类动物的研究文献。ILAR杂志第45卷第2期2004年的文章中审查的结果进行了评估的范围和问题与疾病的实体在妇女。非人灵长类动物的研究与已知的信息，关于妇女的疾病进行了讨论，并强调了人类疾病的研究的动物模型的效用，基于其显着的相关性，由于非人灵长类动物和人类受试者的生理，代谢和治疗干预的反应的相似性。动物模型的其他优点包括控制实验环境的能力和进行慢性研究程序的能力。这些发现使我们能够利用非人灵长类动物作为动物世界中最相关的模型来研究人类疾病过程。
This overview of the current status of medical problems that affect women is related to current studies on pathophysiology and therapeutic interventions using nonhuman primates to demonstrate the utility of the primate model for the study of disease processes in women. The current medical literature on women's health is compared with the literature on nonhuman primate research. The findings reviewed in the articles of ILAR Journal Volume 45 Issue 2 of 2004 are evaluated in the context of the scope and problems associated with disease entities in women. Nonhuman primate research with known information regarding women's disease is discussed, and the utility of the animal model for the study of human disease is highlighted, based on its significant relevance due to similarities of nonhuman primate and human subjects' physiology, metabolism, and responses to therapeutic interventions. Additional advantages of the animal model include the ability to control the experimental environment and the capacity to perform chronic study procedures. These findings allow us to utilize the nonhuman primate as the most relevant model in the animal world for the study of human disease processes.