Simultaneous voltammetric determination of dopamine and uric acid based on Langmuir-Blodgett film of calixarene modified glassy carbon electrode
Simultaneous voltammetric determination of dopamine and uric acid based on Langmuir-Blodgett film of calixarene modified glassy carbon electrode
复制标题
基于杯芳烃修饰玻碳电极Langmuir-Blodgett膜同时伏安法测定多巴胺和尿酸
DOI：
10.1016/j.snb.2015.06.155
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发表时间：
2015-12-31
影响因子：
8.4
通讯作者：
Ye, Baoxian
中科院分区：
文献类型：
--
作者：
Wang, Fei;Chi, Chang Long;Ye, Baoxian
将C-十一烷基杯[4]间苯二酚芳烃（CUCR）的LB膜作为分子受体，预处理的玻碳电极（GCE）作为电子传递增强剂，集成到电化学传感器系统中。这种新型电化学传感器具有杯芳烃的高超分子识别和富集能力以及预处理过的GCE的大比表面积和高活性中心的特性。在该电极上，多巴胺（DA）和尿酸（UA）的峰电流较裸电极和预处理电极显著增加，这是由于CUCR LB膜和预处理电极的协同作用。利用差示脉冲伏安法，将所得电极用于研制高灵敏度的电化学传感器，首次在抗坏血酸（AA）存在下同时测定DA和UA。在选定的条件下，DA和UA的线性响应范围分别为8.0 × 10（-8）~ 6.0 × 10（-6）mol L-1和4.0 × 10（-7）~ 4.0 × 10（-5）mol L-1，检出限分别为2.0 × 10（-8）mol L-1和8.0 × 10（-8）mol L-1。此外，该电极还表现出良好的选择性、稳定性和重现性。(C)2015 Elsevier B. V.版权所有。
Langmuir-Blodgett (LB) film of C-Undecylcalix[4]resorcinarene (CUCR) as molecular receptor and pretreated glassy carbon electrode (GCE) as enhancer of electron transfer are integrated in the electrochemical sensor system. The new electrochemical sensor possesses the properties of calixarene (high supramolecular recognition and enrichment capability) and pretreated GCE (large surface area and high active sites). At the resulting electrode, the peak current of dopamine (DA) and uric acid (UA) increased dramatically compared with that on the bare GCE and pretreated GCE which due to the synergetic effects of LB film of CUCR and pretreated GCE. Using differential pulse voltammetry, the resulting electrode was applied to develop a high sensitive electrochemical sensor for the simultaneous determination of DA and UA in the presence of ascorbic acid (AA) for the first time. Under the selected conditions, the linear response ranges for DA and UA are 8.0 x 10(-8) to 6.0 x 10(-6) mol L-1 and 4.0 x 10(-7) to 4.0 x 10(-5) mol L-1 with the detection limits of 2.0 x 10(-8) mol L-1 and 8.0 x 10(-8) mol L-1, respectively. Besides, the resulting electrode also showed an excellent selectivity, stability and reproducibility. (C) 2015 Elsevier B.V. All rights reserved.